Archive | August, 2005

Targeting cannabinoid receptors to treat leukemia: role of cross-talk between extrinsic and intrinsic pathways in Delta9-tetrahydrocannabinol (THC)-induced apoptosis of Jurkat cells.

2005 Aug;29(8):915-22. Epub 2005 Mar 2. Targeting cannabinoid receptors to treat leukemia: role of cross-talk between extrinsic and intrinsic pathways in Delta9-tetrahydrocannabinol (THC)-induced apoptosis of Jurkat cells. Lombard C1, Nagarkatti M, Nagarkatti PS. Author information Abstract Targeting cannabinoid receptors has recently been shown to trigger apoptosis and offers a novel treatment modality against malignancies of the immune system. However, the precise mechanism of apoptosis in […]

Cannabinoids and ceramide: two lipids acting hand-by-hand.

2005 Aug 19;77(14):1723-31. Cannabinoids and ceramide: two lipids acting hand-by-hand. Velasco G1, Galve-Roperh I, Sánchez C, Blázquez C, Haro A, Guzmán M. Author information Abstract Cannabinoids, the active components of Cannabis sativa (marijuana) and their endogenous counterparts, exert their effects by binding to specific G-protein-coupled receptors that modulate adenylyl cyclase and ion channels. Recent research has shown that the CB1 cannabinoid receptor […]