Archive | October, 2005

Guidelines for the use of cannabinoid compounds in chronic pain.

 2005 Autumn;10 Suppl A:44A-6A. Clark AJ, Lynch ME, Ware M, Beaulieu P, McGilveray IJ, Gourlay D. Author information Abstract OBJECTIVE: To provide clinicians with guidelines for the use of cannabinoid compounds in the treatment of chronic pain. METHODS: Publications indexed from 1990 to 2005 in the National Library of Medicine Index Medicus were searched through PubMed. A consensus concerning these guidelines was achieved by the authors through review and […]

Cannabis and tobacco smoke are not equally carcinogenic

Harm Reduct J. 2005; 2: 21. Published online 2005 October 18. doi:  10.1186/1477-7517-2-21 PMCID: PMC1277837 Cannabis and tobacco smoke are not equally carcinogenic Robert Melamede1,2 Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract More people are using the cannabis plant as modern basic and clinical science reaffirms and extends its medicinal […]

Preclinical science regarding cannabinoids as analgesics: an overview.

2005 Autumn;10 Suppl A:7A-14A. Preclinical science regarding cannabinoids as analgesics: an overview. Lynch ME. Author information Abstract Modern pharmacology of cannabinoids began in 1964 with the isolation and partial synthesis of delta-9-tetrahydrocannabinol, the main psycho-active agent in herbal cannabis. Since then, potent antinociceptive and antihyperalgesic effects of cannabinoid agonists in animal models of acute and […]

Mother’s milk and the muffin man: grassroots innovations in medical marijuana delivery systems.

 2005;4(3-4):183-204. Mother’s milk and the muffin man: grassroots innovations in medical marijuana delivery systems. Chapkis W1, Webb RJ. Author information  Abstract In the ongoing debates over medical marijuana, opponents often conflate the alleged risks of cannabis therapeutics with the acknowledged harms associated with smoking. Although smoking is the most widely used method of administering marijuana, it is not the only […]

Mother’s Milk and the Muffin Man

2005;4(3-4):183-204. Mother’s milk and the muffin man: grassroots innovations in medical marijuana delivery systems. Chapkis W1, Webb RJ. Author information  Abstract In the ongoing debates over medical marijuana, opponents often conflate the alleged risks of cannabis therapeutics with the acknowledged harms associated with smoking. Although smoking is the most widely used method of administering marijuana, it is not the […]

Cannabinoids and cancer.

2005 Oct;5(10):941-52. Cannabinoids and cancer. Kogan NM1. Author information Abstract Marijuana has been used in medicine for millennia, but it was not until 1964 that delta9-tetrahydrocannabinol (delta9-THC), its major psychoactive component, was isolated in pure form and its structure was elucidated. Shortly thereafter it was synthesized and became readily available. However, it took another decade […]

A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.

2006;66(2):234-46. Epub 2005 Oct 4. A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. Russo E1, Guy GW. Author information Abstract This study examines the current knowledge of physiological and clinical effects of tetrahydrocannabinol (THC) and cannabidiol (CBD) and presents a rationale for their combination in pharmaceutical preparations. Cannabinoid and vanilloid receptor effects as well as […]