Archive | June, 2009

Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans.

 2009 Jun 30;79(5):333-7. doi: 10.1016/j.brainresbull.2009.01.011. Epub 2009 Feb 6. Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans. Schley M1, Ständer S, Kerner J, Vajkoczy P, Schüpfer G, Dusch M, Schmelz M, Konrad C. Author information Abstract BACKGROUND AND OBJECTIVES: The most abundant malignant brain tumor in human is glioblastoma and patients with this type of tumor have a poor […]

The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi’s sarcoma cells in vitro.

 2009 Aug 15;616(1-3):16-21. doi: 10.1016/j.ejphar.2009.06.004. Epub 2009 Jun 17. The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi’s sarcoma cells in vitro. Luca T1, Di Benedetto G, Scuderi MR, Palumbo M, Clementi S, Bernardini R, Cantarella G. Author information Abstract Kaposi’s sarcoma is a highly vascularized mesenchymal neoplasm arising with multiple lesions of the skin. Endogenous cannabinoids have been shown to inhibit proliferation of […]

Time-dependent vascular actions of cannabidiol in the rat aorta.

2009 Jun 10;612(1-3):61-8. doi: 10.1016/j.ejphar.2009.03.010. Epub 2009 Mar 11. Time-dependent vascular actions of cannabidiol in the rat aorta. O’Sullivan SE1, Sun Y, Bennett AJ, Randall MD, Kendall DA. Author information  Abstract We have shown that the major active agent of Cannabis sativa, Delta(9)-tetrahydrocannabinol, activates peroxisome proliferator-activated receptor gamma [PPARgamma, O’Sullivan, S.E., Tarling, E.J., Bennett, A.J., Kendall, D.A., Randall, M.D., […]

Effects of gibberellic acid on primary terpenoids and delta-tetrahydrocannabinol in Cannabis sativa at flowering stage.

2009 Jun;51(6):553-61. doi: 10.1111/j.1744-7909.2009.00833.x. Effects of gibberellic acid on primary terpenoids and delta-tetrahydrocannabinol in Cannabis sativa at flowering stage. Mansouri H1, Asrar Z, Mehrabani M. Author information Abstract Plants synthesize an astonishing diversity of isoprenoids, some of which play essential roles in photosynthesis, respiration, and the regulation of growth and development. Two independent pathways for the biosynthesis […]