Archive | April, 2010

NSAIDs, Opioids, Cannabinoids and the Control of Pain by the Central Nervous System.

2010 Apr 29;3(5):1335-1347. Vanegas H1, Vazquez E2, Tortorici V3. Author information Abstract Nonsteroidal anti-inflammatory drugs (NSAIDs) act upon peripheral tissues and upon the central nervous system to produce analgesia. A major central target of NSAIDs is the descending pain control system. The rostral structures of the descending pain control system send impulses towards the spinal cord and […]

A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis.

2010 Apr;28(2):115-23. doi: 10.1007/s10637-009-9221-0. Epub 2009 Feb 3. A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis. Cozzolino R1, Calì G, Bifulco M, Laccetti P. Author information Abstract The active components of Cannabis sativa and their derivatives produce a wide spectrum of effects, some of which may have clinical application. […]

“Divine Stramonium”: The Rise and Fall of Smoking for Asthma

Journal List > Med Hist > v.54(2); 2010 Apr > PMC2844275 Med Hist. 2010 Apr; 54(2): 171–194. PMCID: PMC2844275 MARK JACKSON* Author information ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Introduction On the evening of Saturday 31 August 1901, the celebrated French novelist Marcel Proust wrote to his mother with […]

Activation of cannabinoid receptor CB2 regulates osteogenic and osteoclastogenic gene expression in human periodontal ligament cells.

2010 Aug;45(4):504-11. doi: 10.1111/j.1600-0765.2009.01265.x. Epub 2010 Apr 19. Activation of cannabinoid receptor CB2 regulates osteogenic and osteoclastogenic gene expression in human periodontal ligament cells. Qian H1, Zhao Y, Peng Y, Han C, Li S, Huo N, Ding Y, Duan Y, Xiong L, Sang H. Author information Abstract BACKGROUND AND OBJECTIVE: Cannabinoid receptor CB2, expressed in osteoblasts and osteoclasts, plays a crucial role in the […]

Involvement of the endocannabinoid system in periodontal healing.

 2010 Apr 16;394(4):928-33. doi: 10.1016/j.bbrc.2010.03.080. Epub 2010 Mar 15. Kozono S1, Matsuyama T, Biwasa KK, Kawahara K, Nakajima Y, Yoshimoto T, Yonamine Y, Kadomatsu H, Tancharoen S, Hashiguchi T, Noguchi K, Maruyama I. Author information Abstract Endocannabinoids including anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are important lipid mediators for immunosuppressive effects and for appropriate homeostasis via their G-protein-coupled cannabinoid (CB) receptors in mammalian organs and tissues, and […]