Archive | June, 2010

CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model

Br J Pharmacol. Jun 2010; 160(3): 657–668. doi:  10.1111/j.1476-5381.2010.00769.x PMCID: PMC2931565 CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model Partha Mukhopadhyay,1,# Hao Pan,1,2,# Mohanraj Rajesh,1 Sándor Bátkai,1 Vivek Patel,1 Judith Harvey-White,1 Bani Mukhopadhyay,1 György Haskó,3 Bin Gao,1 Ken Mackie,4 and Pál Pacher1 Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Background and purpose: […]

Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

Cell Commun Signal. 2010; 8: 12. Published online 2010 June 17. doi:  10.1186/1478-811X-8-12 PMCID: PMC2898685 Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis Susanne A Wolf,1,2 Anika Bick-Sander,1 Klaus Fabel,4 Perla Leal-Galicia,4 Svantje Tauber,2Gerardo Ramirez-Rodriguez,1,3 Anke Müller,1 Andre Melnik,2 Tim P Waltinger,2 Oliver Ullrich,2and Gerd Kempermann1,4 Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: […]

Novel natural and synthetic ligands of the endocannabinoid system.

2010;17(14):1341-59. Novel natural and synthetic ligands of the endocannabinoid system. Hanus LO1, Mechoulam R. Author information Abstract In this review we describe recent advances in the chemistry of novel CB(1)/CB(2) agonists, CB(1) antagonists, selective CB(2) agonists, fatty acid amide hydrolase inibitors, monoglyceride (MGL) and diglyceride (DAGL) inhibitors and cannabinoid-type agonists and antagonists of non CB(1)/CB(2) receptors. […]

The health and safety of children living in marijuana grow operations : a child welfare perspective

Douglas, Janet 2010  This dissertation examines the health and safety of children found living in marijuana grow operations in two key regions in British Columbia, and how child protection workers have been drawn into this phenomenon. Data was collected on the physical and health characteristics of the grow operation homes, as well as on the […]

Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas.

 2010 May-Jun;56(6-7):829-33. doi: 10.1016/j.neuint.2010.03.007. Epub 2010 Mar 20. Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas. De Jesús ML1, Hostalot C, Garibi JM, Sallés J, Meana JJ, Callado LF. Author information Abstract Gliomas are the most important group of malignant primary brain tumors and one of the most aggressive forms of cancer. During the last years, several studies have demonstrated […]

The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice.

Br J Pharmacol. 2010 June; 160(3): 677–687. doi:  10.1111/j.1476-5381.2010.00756.x PMCID: PMC2931567 The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice Daniele Bolognini,1,2 Barbara Costa,3 Sabatino Maione,4 Francesca Comelli,3 Pietro Marini,1 Vincenzo Di Marzo,5 Daniela Parolaro,2 Ruth A Ross,1 Lisa A Gauson,1 Maria G Cascio,1 and Roger G Pertwee1 Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract […]

Cannabinoids inhibit cellular respiration of human oral cancer cells.

2010;85(6):328-35. doi: 10.1159/000312686. Epub 2010 Jun 2. Cannabinoids inhibit cellular respiration of human oral cancer cells. Whyte DA1, Al-Hammadi S, Balhaj G, Brown OM, Penefsky HS, Souid AK. Author information  Abstract BACKGROUND AND PURPOSE: The primary cannabinoids, Delta(9)-tetrahydrocannabinol (Delta(9)-THC) and Delta(8)-tetrahydrocannabinol (Delta(8)-THC) are known to disturb the mitochondrial function and possess antitumor activities. These observations prompted us to investigate their […]