Archive | July, 2010

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

Mol Cancer. 2010; 9: 196. Published online 2010 July 22. doi:  10.1186/1476-4598-9-196 PMCID: PMC2917429 Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition María M Caffarel,1,6 Clara Andradas,1 Emilia Mira,2 Eduardo Pérez-Gómez,1 Camilla Cerutti,1,6 Gema Moreno-Bueno,3 Juana M Flores,4 Isabel García-Real,4 José Palacios,5Santos Mañes,2 Manuel Guzmán,1 and Cristina Sánchez1 Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Background ErbB2-positive breast cancer is […]

Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids

Blood. Jul 22, 2010; 116(3): 456–465.  Prepublished online Mar 19, 2010. doi:  10.1182/blood-2010-01-260372 PMCID: PMC2913454 Red Cells, Iron, and Erythropoiesis Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids Divyanshoo R. Kohli,1,* Yunfang Li,1,* Sergey G. Khasabov,2 Pankaj Gupta,3 Lois J. Kehl,4Marna E. Ericson,5 Julia Nguyen,1 Vinita Gupta,6 Robert P. Hebbel,1 Donald A. Simone,2and  Kalpna Gupta1 Author information ► Article notes ► Copyright and License information ► This […]

Cannabinoid and cannabinoid-like receptors in microglia, astrocytes and astrocytomas

Glia. Author manuscript; available in PMC 2011 July 1. Published in final edited form as: Glia. 2010 July; 58(9): 1017–1030. doi:  10.1002/glia.20983 PMCID:PMC2919281 NIHMSID:NIHMS221091 Cannabinoid and cannabinoid-like receptors in microglia, astrocytes and astrocytomas Nephi Stella Author information ► Copyright and License information ► The publisher’s final edited version of this article is available at Glia See other articles in PMC that cite the published […]

Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke.

2010 Jul 8;3(7):2197-2212. Hayakawa K1, Mishima K2, Fujiwara M3. Author information Abstract Cannabis contains the psychoactive component delta⁸-tetrahydrocannabinol (delta⁸-THC), and the non-psychoactive components cannabidiol (CBD), cannabinol, and cannabigerol. It is well-known that delta⁸-THC and other cannabinoid CB₁ receptor agonists are neuroprotective during global and focal ischemic injury. Additionally, delta⁸-THC also mediates psychological effects through the activation of the CB₁ […]

Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion

Br J Pharmacol. 2010 July; 160(5): 1234–1242. doi:  10.1111/j.1476-5381.2010.00755.x PMCID: PMC2936031 Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion Sarah K Walsh,1 Claire Y Hepburn,1 Kathleen A Kane,2 and Cherry L Wainwright1 Author information ► Article notes ► Copyright and License information ► Go to: Abstract Background and purpose: Cannabidiol (CBD) is a phytocannabinoid, with anti-apoptotic, anti-inflammatory and antioxidant effects […]