Archive | August, 2011

Cannabis in palliative medicine: improving care and reducing opioid-related morbidity.

 2011 Aug;28(5):297-303. doi: 10.1177/1049909111402318. Epub 2011 Mar 28. Carter GT1, Flanagan AM, Earleywine M, Abrams DI, Aggarwal SK, Grinspoon L. Author information Abstract Unlike hospice, long-term drug safety is an important issue in palliative medicine. Opioids may produce significant morbidity. Cannabis is a safer alternative with broad applicability for palliative care. Yet the Drug Enforcement Agency (DEA) classifies cannabis as […]

Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects

Br J Pharmacol. 2011 August; 163(7): 1344–1364. doi:  10.1111/j.1476-5381.2011.01238.x PMCID: PMC3165946 Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects Ethan B Russo Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesized it. […]

The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction

Pharmaceuticals (Basel). Aug 2011; 4(8): 1101–1136.  Published online Aug 10, 2011. doi:  10.3390/ph4081101 PMCID: PMC4058662 The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction Maria-Paz Viveros,1,* Francisco-Javier Bermúdez-Silva,2,3 Ana-Belén Lopez-Rodriguez,1 and  Edward J. Wagner4 Author information ► Article notes ► Copyright and License information ► Go to: Abstract The endocannabinoid system (ECS) has been […]

Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice.

Br J Pharmacol. Aug 2011; 163(7): 1507–1519. doi:  10.1111/j.1476-5381.2011.01379.x PMCID: PMC3165959 Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice Ewa Kozela,1,* Nirit Lev,2,* Nathali Kaushansky,3 Raya Eilam,4 Neta Rimmerman,5 Rivka Levy,5 Avraham Ben-Nun,3 Ana Juknat,1,* and Zvi Vogel1,5,* Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract BACKGROUND AND PURPOSE Cannabis extracts […]

Endocannabinoids and traumatic brain injury

Br J Pharmacol. 2011 August; 163(7): 1402–1410. doi:  10.1111/j.1476-5381.2011.01343.x PMCID: PMC3165950 Endocannabinoids and traumatic brain injury Esther Shohami, Ayelet Cohen-Yeshurun, Lital Magid, Merav Algali, and Raphael Mechoulam Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Traumatic brain injury (TBI) represents the leading cause of death in young individuals. It triggers the accumulation of harmful […]

Do Cannabinoids have a therapeutic role in transplantation?

Trends Pharmacol Sci. Author manuscript; available in PMC 2011 August 1. Published in final edited form as: Trends Pharmacol Sci. 2010 August; 31(8): 345–350. Published online 2010 June 28. doi:  10.1016/j.tips.2010.05.006 PMCID: PMC2923447 NIHMSID: NIHMS211255 Do Cannabinoids have a therapeutic role in transplantation? Mitzi Nagarkatti,* Sadiye Amcaoglu Rieder,*+ Venkatesh Hegde,*+ Shunsuke Kanada,*+ andPrakash Nagarkatti* Author information ► Copyright and License information ► The publisher’s final edited version of […]