Archive | March, 2012

Extract from Cannabis sativa — Benefit Assessment According to §35a Social Code Book V [Internet].

Format: Abstract Send to Editors Institute for Quality and Efficiency in Health Care. Source Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2012 Mar. Extract of Dossier Assessment No. A12-01. IQWiG Dossier Assessment Extracts. Excerpt In the following, “extract from Cannabis sativa” will be referred to by “THC/CBD”. The present benefit assessment of THC/CBD […]

Design of a Potent CB1 Receptor Antagonist Series: Potential Scaffold for Peripherally-Targeted Agents.

 2012 Mar 21;3(5):397-401. doi: 10.1021/ml3000325. eCollection 2012. Design of a Potent CB1 Receptor Antagonist Series: Potential Scaffold for Peripherally-Targeted Agents. Dow RL, Carpino PA, Gautreau D, Hadcock JR, Iredale PA, Kelly-Sullivan D, Lizano JS, O’Connor RE, Schneider SR, Scott DO, Ward KM. Author information Abstract Antagonism of cannabinoid-1 (CB1) receptor signaling has been demonstrated to inhibit feeding behaviors in humans, but CB1-mediated central nervous system (CNS) […]

Contributions of endocannabinoid signaling to psychiatric disorders in humans: Genetic and biochemical evidence

Neuroscience. Author manuscript; available in PMC 2013 March 1. Published in final edited form as: Neuroscience. 2012 March 1; 204: 207–229. Published online 2011 November 17.doi:  10.1016/j.neuroscience.2011.11.020 PMCID: PMC3288440 NIHMSID: NIHMS339627 Contributions of endocannabinoid signaling to psychiatric disorders in humans: Genetic and biochemical evidence Cecilia J. Hillard, Kenneth M. Weinlander, and Kara L. Stuhr Author information ► Copyright and License information ► The publisher’s final […]

Effect of feeding hemp seed and hemp seed oil on laying hen performance and egg yolk fatty acid content: evidence of their safety and efficacy for laying hen diets.

2012 Mar;91(3):701-11. doi: 10.3382/ps.2011-01825. Effect of feeding hemp seed and hemp seed oil on laying hen performance and egg yolk fatty acid content: evidence of their safety and efficacy for laying hen diets. Gakhar N1, Goldberg E, Jing M, Gibson R, House JD. Author information Abstract Forty-eight 19-wk-old Bovan White laying hens were fed 1 of 5 diets containing either hemp […]

[Effects of anandamide on IL-11 production through the TRPV1 of human periodontal ligament cells].

2012 Mar;79(1):7-14. [Article in Japanese] Haruta C1. Author information Abstract A functional endocannabinoid system is present in several mammalian organs and tissues. The endogenous cannabinoid anandamide (AEA) is a bioactive lipid neurotransmitter that is present in a variety of tissues and has multiple functions. Recently, this cannabinoid system was reported to play important roles in osteoblastic and osteoclastic cells. Human periodontal ligament […]