Archive | November, 2012

Photochemical trans-/cis-isomerization and quantitation of zearalenone in edible oils.

2012 Nov 28;60(47):11733-40. doi: 10.1021/jf3037775. Epub 2012 Nov 19. Photochemical trans-/cis-isomerization and quantitation of zearalenone in edible oils. Köppen R1, Riedel J, Proske M, Drzymala S, Rasenko T, Durmaz V, Weber M, Koch M. Author information Abstract The emphasis of the present work was to investigate the photochemical conversion of trans- to cis-zearalenone in edible oils under real-life conditions. For quantitation purposes […]

Why small-scale cannabis growers stay small: five mechanisms that prevent small-scale growers from going large scale.

2012 Nov;23(6):458-64. doi: 10.1016/j.drugpo.2012.08.001. Epub 2012 Oct 1. Why small-scale cannabis growers stay small: five mechanisms that prevent small-scale growers from going large scale. Hammersvik E1, Sandberg S, Pedersen W. Author information Abstract BACKGROUND: Over the past 15-20 years, domestic cultivation of cannabis has been established in a number of European countries. New techniques have made such […]

Cannabinoids: a new hope for breast cancer therapy?

Cannabinoids: a new hope for breast cancer therapy? Caffarel MM, Andradas C, Pérez-Gómez E, Guzmán M, Sánchez C. Source Dept. Biochemistry and Molecular Biology I, School of Biology, Complutense University-CIBERNED-IRYCIS, Madrid, Spain. Abstract Breast cancer is a very common disease that affects approximately 1 in 10 women at some point in their lives. Importantly, breast cancer cannot be considered a single disease as it is […]

The promise and dilemma of cannabinoid therapy: lessons from animal studies of bone disease.

Bonekey Rep. 2012; 1: 224. Published online Nov 21, 2012. doi:  10.1038/bonekey.2012.224 PMCID: PMC3868875 The promise and dilemma of cannabinoid therapy: lessons from animal studies of bone disease Aymen I Idrisa,1 Author information ► Article notes ► Copyright and License information ► Go to: Abstract The endocannabinoid system plays an important role in numerous physiological processes and represents a potential drug target for diseases ranging […]

Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.

Toxicol Lett. Author manuscript; available in PMC May 5, 2014. Published in final edited form as: Toxicol Lett. Nov 15, 2012; 214(3): 314–319. Published online Sep 8, 2012. doi:  10.1016/j.toxlet.2012.08.029 PMCID: PMC4009504 NIHMSID: NIHMS575321 Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration Shuso Takeda,a Shunsuke Okajima,a Hiroko Miyoshi,a Kazutaka Yoshida,a Yoshiko Okamoto,a Tomoko Okada,bToshiaki Amamoto,c Kazuhito […]

Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55.

2012 Nov 14;4(1):41-5. doi: 10.1021/ml300235q. eCollection 2013. Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55. Rempel V1, Fuchs A1, Hinz S1, Karcz T1, Lehr M2, Koetter U3, Müller CE1. Author information Abstract The bark of Magnolia officinalis is used in Asian traditional medicine for the treatment of anxiety, sleeping disorders, and allergic diseases. We found […]

Endocannabinoids and the renal proximal tubule: an emerging role in diabetic nephropathy.

 2012 Nov;44(11):2028-31. doi: 10.1016/j.biocel.2012.07.008. Epub 2012 Jul 27. Endocannabinoids and the renal proximal tubule: an emerging role in diabetic nephropathy. Jenkin KA1, Verty AN, McAinch AJ, Hryciw DH. Author information Abstract Diabetic nephropathy is a leading cause for the development of end-stage renal disease. In diabetes mellitus, a number of structural changes occur within the kidney which leads to a decline […]