Archive | April, 2013

Sheep cheese naturally enriched in α-linolenic, conjugated linoleic and vaccenic acids improves the lipid profile and reduces anandamide in the plasma of hypercholesterolaemic subjects.

2013 Apr 28;109(8):1453-62. doi: 10.1017/S0007114512003224. Epub 2012 Aug 24. Sheep cheese naturally enriched in α-linolenic, conjugated linoleic and vaccenic acids improves the lipid profile and reduces anandamide in the plasma of hypercholesterolaemic subjects. Pintus S1, Murru E, Carta G, Cordeddu L, Batetta B, Accossu S, Pistis D, Uda S, Elena Ghiani M, Mele M, Secchiari P, Almerighi G, Pintus P, Banni S. Author information Abstract Intake of dairy […]

Striatal Molecular Signature of Subchronic Subthalamic Nucleus High Frequency Stimulation in Parkinsonian Rat.

Striatal Molecular Signature of Subchronic Subthalamic Nucleus High Frequency Stimulation in Parkinsonian Rat. Lortet S, Lacombe E, Boulanger N, Rihet P, Nguyen C, Goff LK, Salin P. Source Aix-Marseille Université, CNRS, IBDM UMR 7288, Marseille, France. Abstract This study addresses the molecular mechanisms underlying the action of subthalamic nucleus high frequency stimulation (STN-HFS) in the treatment of Parkinson’s disease and its […]

G-Protein Receptor Kinase 5 Regulates the Cannabinoid Receptor 2-Induced Upregulation of Serotonin 2A Receptors.

[Epub ahead of print] G-Protein Receptor Kinase 5 Regulates the Cannabinoid Receptor 2-Induced Upregulation of Serotonin 2A Receptors. Franklin JM, Carrasco GA. Source University of Kansas, United States. Abstract We have recently reported that cannabinoid agonists can upregulate and enhance the activity of 5-HT2A receptors in prefrontal cortex (PFCx). Increased expression and activity of cortical 5-HT2Areceptors has been associated with neuropsychiatric […]

Glucocorticoid receptors in the prefrontal cortex regulate dopamine efflux to stress via descending glutamatergic feedback to the ventral tegmental area.

[Epub ahead of print] Glucocorticoid receptors in the prefrontal cortex regulate dopamine efflux to stress via descending glutamatergic feedback to the ventral tegmental area. Butts KA, Phillips AG. Source Department of Psychiatry, University of British Columbia, Vancouver, Canada. Abstract Enhanced dopamine (DA) efflux in the medial prefrontal cortex (mPFC) is a well-documented response to acute stress. […]

The prevalence and incidence of medicinal cannabis on prescription in The Netherlands.

. [Epub ahead of print] The prevalence and incidence of medicinal cannabis on prescription in The Netherlands. Hazekamp A, Heerdink ER. Source Department of Plant Metabolomics, Faculty of Science, Leiden University, Leiden, The Netherlands, ahazekamp@rocketmail.com. Abstract BACKGROUND: A growing number of countries are providing pharmaceutical grade cannabis to chronically ill patients. However, little published data is […]

Mechanisms Of Cannabidiol Neuroprotection In Hypoxic-Ischemic Newborn Pigs: Role Of 5HT1A And CB2 Receptors.

[Epub ahead of print] Mechanisms Of Cannabidiol Neuroprotection In Hypoxic-Ischemic Newborn Pigs: Role Of 5HT1A And CB2 Receptors. Pazos MR, Mohammed N, Lafuente H, Santos M, Martínez E, Moreno E, Valdizan E, Romero J, Pazos A, Franco R, Hillard CJ, Alvarez FJ, Martínez-Orgado J. Source Experimental Unit, Pediatric Department, University Hospital Puerta de Hierro Majadahonda, 28222-Madrid, Spain. Abstract The mechanisms underlying the neuroprotective effects of cannabidiol (CBD) […]

The inverse agonist of CB1 receptor SR141716 blocks compulsive eating of palatable food.

. [Epub ahead of print] The inverse agonist of CB1 receptor SR141716 blocks compulsive eating of palatable food. Dore R, Valenza M, Wang X, Rice KC, Sabino V, Cottone P. Source Laboratory of Addictive Disorders, Departments of Pharmacology and Psychiatry, Boston University School of Medicine, Boston, MA, USA. Abstract Dieting and the increased availability of highly palatable food are considered […]

The Genetics of Alcohol and Other Drug Dependence.

The Genetics of Alcohol and Other Drug Dependence. Dick DM Ph D, Agrawal A Ph D. Source Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia. Abstract Alcohol dependence and dependence on other drugs frequently co-occur, and strong evidence suggests that both disorders are, at least in part, influenced by genetic factors. Indeed, […]

Activation-dependent plasticity of polarized GPCR distribution on the neuronal surface.

[Epub ahead of print] Activation-dependent plasticity of polarized GPCR distribution on the neuronal surface. Simon AC, Loverdo C, Gaffuri AL, Urbanski M, Ladarre D, Carrel D, Rivals I, Leterrier C, Benichou O, Dournaud P, Szabo B,Voituriez R, Lenkei Z. Source Laboratoire Neurobiologie, CNRS UMR7637, ESPCI-ParisTech, 10 Rue Vauquelin, 75005 Paris, France. Abstract Directionality of information flow through neuronal networks is sustained, at the cellular level, by […]