Archive | September, 2013

Endocannabinoids and Endovanilloids: A Possible Balance in the Regulation of the Testicular GnRH Signalling.

Endocannabinoids and Endovanilloids: A Possible Balance in the Regulation of the Testicular GnRH Signalling. Chianese R, Ciaramella V, Scarpa D, Fasano S, Pierantoni R, Meccariello R. Source Dipartimento di Medicina Sperimentale Sezione “F. Bottazzi,” Seconda Università di Napoli, Via Costantinopoli 16, 80138 Napoli, Italy. Abstract Reproductive functions are regulated both at central (brain) and gonadal levels. In this respect, the endocannabinoid […]

Targeting the endocannabinoid system to treat haunting traumatic memories

Targeting the endocannabinoid system to treat haunting traumatic memories Irit Akirav* Department of Psychology, University of Haifa, Haifa, Israel A commentary on The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD) by Trezza, V., and Campolongo, P. (2013). Front. Behav. Neurosci. 7:100. doi: 10.3389/fnbeh.2013.00100 […]

Modulation of the Endocannabinoid System: Vulnerability Factor and New Treatment Target for Stimulant Addiction.

Journal List > Front Psychiatry > v.4; 2013 > PMC3780360 Front Psychiatry. 2013; 4: 109.  Published online 2013 Sep 23. doi:  10.3389/fpsyt.2013.00109 PMCID: PMC3780360 Stéphanie Olière,1 Antoine Jolette-Riopel,1 Stéphane Potvin,2,3 and  Didier Jutras-Aswad1,2,* Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Cannabis is one of the most widely used illicit substance among users of stimulants such as cocaine and […]

Cannabinoid Transmission in the Prelimbic Cortex Bidirectionally Controls Opiate Reward and Aversion Signaling through Dissociable Kappa Versus μ-Opiate Receptor Dependent Mechanisms.

Cannabinoid Transmission in the Prelimbic Cortex Bidirectionally Controls Opiate Reward and Aversion Signaling through Dissociable Kappa Versus μ-Opiate Receptor Dependent Mechanisms. Ahmad T, Lauzon NM, de Jaeger X, Laviolette SR. Source Departments of Anatomy and Cell Biology, Psychiatry, and Psychology, The Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada N5Y 5T8. Abstract Cannabinoid, dopamine […]

Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib.

[Epub ahead of print] Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Windsor MA, Valk PL, Xu S, Banerjee S, Marnett LJ. Source A.B. Hancock Jr. Memorial Laboratory for Cancer Research, Department of Biochemistry, Department of Chemistry, Department of Pharmacology, Vanderbilt Institute of Chemical Biology, Center in Molecular Toxicology, and Vanderbilt-Ingram Cancer Center, Vanderbilt University School […]

Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2 receptors.

[Epub ahead of print] Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2 receptors. Teodoro R, Moldovan RP, Lueg C, Günther R, Donat CK, Ludwig FA, Fischer S, Deuther-Conrad W, Wünsch B, Brust P. Abstract BACKGROUND: The level of expression of cannabinoid receptor type 2 (CB2R) in healthy and diseased brain has not been fully elucidated. Therefore, there is a growing interest […]

PPARγ mediates the effects of WIN55,212-2, an synthetic cannabinoid, on the proliferation and apoptosis of the BEL-7402 hepatocarcinoma cells.

[Epub ahead of print] PPARγ mediates the effects of WIN55,212-2, an synthetic cannabinoid, on the proliferation and apoptosis of the BEL-7402 hepatocarcinoma cells. Hong Y, Zhou Y, Wang Y, Xiao S, Liao DJ, Zhao Q. Source Department of Biochemistry, Guangzhou Medical University, Guangzhou, 510182, China. Abstract Cannabis sativa has long been used as a traditional medicine in China. Among its effective […]

Differential expression and functional role of cannabinoid genes in alcohol users.

 [Epub ahead of print] Differential expression and functional role of cannabinoid genes in alcohol users. Agudelo M, Yndart A, Morrison M, Figueroa G, Muñoz K, Samikkannu T, Nair MP. Source Florida International University, United States. Electronic address: magudelo@fiu.edu. Abstract BACKGROUND: Genetic factors account for about fifty percent of the risk for alcoholism and alcohol dependence (AD) has been reported to be influenced by cannabinoid receptors […]

The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice.

 [Epub ahead of print] The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice. Paula-Freire LI, Andersen ML, Gama VS, Molska GR, Carlini EL. Source Departamento de Psicobiologia, Universidade Federal de São Paulo, Brazil. Electronic address: lyviabiologia@gmail.com. Abstract Trans-caryophyllene is a sesquiterpene present in many medicinal plants’ essential oils, such as Ocimum gratissimum and Cannabis sativa. In […]