Archive | June, 2017

Unity – Community – Cannabis & Love

Friday set the scene for the after party of Winnipeg’s first Unity Cup which followed the Meet and Greet held earlier at WEEDS Glass & Gifts. Those in attendance also celebrated Mat M’s. of WEEDS Winnipeg’s 50th birthday! Happy Birthday Mat!!! The after party at Nectars Nightclub was a yabbin’ dabbin’ due time! OneLove. Over 275 tickets were sold […]

Fundamentals of and Critical Issues in Lipid Autacoid Medicine: A Review.

Pain Ther. 2017 Jun 19. doi: 10.1007/s40122-017-0075-4. [Epub ahead of print] Keppel Hesselink JM1. Author information Abstract The identification of a number of families of lipid signal molecules since the 1990s created new therapeutic possibilities for a great number of disorders characterized by chronic inflammation and pain. These lipid autacoids have been explored in a […]

Changes in hemp secondary fiber production related to technical fiber variability revealed by light microscopy and attenuated total reflectance Fourier transform infrared spectroscopy.

PLoS One. 2017 Jun 22;12(6):e0179794. doi: 10.1371/journal.pone.0179794. eCollection 2017. Fernandez-Tendero E1,2,3, Day A2,3, Legros S4, Habrant A1, Hawkins S2, Chabbert B1. Author information Abstract Interest in hemp (Cannabis sativa L.) is increasing due to the development of a new range of industrial applications based on bast fibers. However the variability of bast fiber yield and […]

Cannabinoids in Pediatrics.

J Pediatr Pharmacol Ther. 2017 May-Jun;22(3):176-185. doi: 10.5863/1551-6776-22.3.176. Campbell CT, Phillips MS, Manasco K. Abstract Despite its controversial nature, the use of medical marijuana and cannabis-derived medicinal products grows more popular with each passing year. As of November 2016, over 40 states have passed legislation regarding the use of either medical marijuana or cannabidiol products. […]


Antioxid Redox Signal. 2017 Jun 22. doi: 10.1089/ars.2016.6958. [Epub ahead of print] Catani MV1, Gasperi V2, Bisogno T3,4, Maccarrone M5,6. Author information Abstract Under physiological conditions, neurons and glia are in a healthy, redox-balanced environment; when injury perturbs this equilibrium, a neuroinflammatory state is established by activated microglia that triggers pro-inflammatory responses and alters the […]

A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.

EMBO J. 2017 Jun 21. pii: e201695347. doi: 10.15252/embj.201695347. [Epub ahead of print] Malenczyk K1,2, Girach F1, Szodorai E1, Storm P3, Segerstolpe Å4, Tortoriello G2, Schnell R5, Mulder J6, Romanov RA1,2, Borók E7, Piscitelli F8, Di Marzo V8, Szabó G9, Sandberg R4, Kubicek S10, Lubec G11, Hökfelt T2, Wagner L12, Groop L3, Harkany T13,2. Author […]

Is cannabis treatment for anxiety, mood, and related disorders ready for prime time?

Depress Anxiety. 2017 Jun 21. doi: 10.1002/da.22664. [Epub ahead of print] Turna J1,2, Patterson B1,3, Van Ameringen M1,3,4. Author information Abstract Anxiety and related disorders are the most common mental conditions affecting the North American population. Despite their established efficacy, first-line antidepressant treatments are associated with significant side effects, leading many afflicted individuals to seek […]

Serum endocannabinoids in assessing pain in patients with chronic pancreatitis and in those with pancreatic ductal adenocarcinoma.

Scand J Gastroenterol. 2017 Jun 20:1-7. doi: 10.1080/00365521.2017.1342139. [Epub ahead of print] Pezzilli R1, Ciuffreda P2, Ottria R2, Ravelli A3, Melzi d’Eril G4, Barassi A4. Author information Abstract BACKGROUND: The endocannabinoid system plays a substantial role in analgesia. AIM: To analyze N-arachidonoylethanolamine (AEA), N-oleoylethanolamine (OEA), linoleoyl ethanolamide (LEA), α-linoleoyl ethanolamine (α-LNEA), N-palmitoylethanolamine (PEA) and N-stearoyl […]

Remote memories are enhanced by COMT activity through dysregulation of the endocannabinoid system in the prefrontal cortex.

Mol Psychiatry. 2017 Jun 20. doi: 10.1038/mp.2017.126. [Epub ahead of print] Scheggia D1, Zamberletti E2, Realini N3, Mereu M1,4, Contarini G4, Ferretti V1, Managò F1, Margiani G5, Brunoro R1, Rubino T2, De Luca MA5, Piomelli D3,6, Parolaro D2, Papaleo F1. Author information Abstract The prefrontal cortex (PFC) is a crucial hub for the flexible modulation […]

Tetrahydrocannabinol (THC) impairs encoding but not retrieval of verbal information.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jun 19. pii: S0278-5846(17)30040-4. doi: 10.1016/j.pnpbp.2017.06.019. [Epub ahead of print] Ranganathan M1, Radhakrishnan R2, Addy PH3, Schnakenberg A2, Williams A2, Carbuto M2, Elander J2, Pittman B4, Andrew Sewell R2, Skosnik PD2, D’Souza DC2. Author information Abstract INTRODUCTION: Cannabis and agonists of the brain cannabinoid receptor (CB1R) produce acute memory impairments […]