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Determination of Acid and Neutral Cannabinoids in Extracts of Different Strains of Cannabis sativa Using GC-FID.

Planta Med. 2017 Dec 13. doi: 10.1055/s-0043-124088. [Epub ahead of print] Ibrahim EA1,2, Gul W1,3, Gul SW3, Stamper BJ3,4, Hadad GM2, Abdel Salam RA2, Ibrahim AK5, Ahmed SA5, Chandra S1, Lata H1, Radwan MM1, ElSohly MA1,3,6. Author information Abstract Cannabis (Cannabis sativa L.) is an annual herbaceous plant that belongs to the family Cannabaceae. Trans-Δ9-tetrahydrocannabinol […]

Salivary endocannabinoids and N-acylethanolamines upon mastication of a semisolid food: implications in fat taste, appetite and food liking.

Food Funct. 2017 Dec 13. doi: 10.1039/c7fo01772c. [Epub ahead of print] Mennella I1, Di Monaco R2, Balazy A1, Ferracane R1, Miele NA3, Cavella S2, Vitaglione P1. Author information Abstract This study aimed to evaluate whether salivary endocannabinoid (EC) and N-acylethanolamine (NAE) concentrations upon mastication of a semisolid food were involved in the sensory perception of […]

Increased levels of circulating fatty acids are associated with protective effects against future cardiovascular events in non-diabetics.

J Proteome Res. 2017 Dec 13. doi: 10.1021/acs.jproteome.7b00671. [Epub ahead of print] Kamleh MA, McLeod O, Checa A, Baldassarre D, Veglia F, Gertow K, Humphries SE, Rauramaa R, deFaire U, Smit AJ, Giral P, Kurl S, Mannarino E, Tremoli E, Silveira A, Orvik J, Hamsten A, Wheelock CE. Abstract Cardiovascular disease (CVD) is a major […]

The status of support for cannabis regulation in Uruguay 4 years after reform: Evidence from public opinion surveys.

Drug Alcohol Rev. 2017 Dec 12. doi: 10.1111/dar.12642. [Epub ahead of print] Cruz JM1, Boidi MF2, Queirolo R3. Author information Abstract INTRODUCTION AND AIMS: The objective of this study was to measure the public support for marijuana legalisation in Uruguay, both overall and in its provisions, in nearly 4 years after its implementation. DESIGN AND METHODS: […]

Provider Perspectives on Use of Medical Marijuana in Children With Cancer.

Pediatrics. 2017 Dec 12. pii: e20170559. doi: 10.1542/peds.2017-0559. [Epub ahead of print] Ananth P1, Ma C2,3, Al-Sayegh H2, Kroon L4,5, Klein V4, Wharton C4, Hallez E6, Braun I3,7, Michelson K6,8, Rosenberg AR4,5,9, London W2,3, Wolfe J2,3,7. Author information Abstract BACKGROUND: Although medical marijuana (MM) may have utility in the supportive care of children with serious […]

Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference.

Sci Rep. 2017 Dec 12;7(1):17410. doi: 10.1038/s41598-017-17796-y. Liu QR1,2, Canseco-Alba A3, Zhang HY4, Tagliaferro P3, Chung M3, Dennis E3, Sanabria B3, Schanz N3, Escosteguy-Neto JC3, Ishiguro H5, Lin Z6, Sgro S3, Leonard CM3, Santos-Junior JG7, Gardner EL4, Egan JM8, Lee JW3, Xi ZX4, Onaivi ES9. Author information Abstract Cannabinoid CB2 receptors (CB2Rs) are expressed in […]

From “Azalla” to Anandamide: Distilling the Therapeutic Potential of Cannabinoids

Rajiv RadhakrishnanCorrespondence information about the author Rajiv RadhakrishnanEmail the author Rajiv Radhakrishnan , David A. Ross Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut PlumX Metrics DOI: http://dx.doi.org/10.1016/j.biopsych.2017.11.017  Abstract > Full Text > Images >References Article Outline Acknowledgments and Disclosures References Root of caper which is on a grave, root of acacia…[and] azalla (cannabis); these seven drugs […]

The endocannabinoid system in cardiovascular function: novel insights and clinical implications.

Clin Auton Res. 2017 Dec 8. doi: 10.1007/s10286-017-0488-5. [Epub ahead of print] Sierra S1,2, Luquin N3, Navarro-Otano J4. Author information Abstract RATIONALE: Cardiovascular disease is now recognized as the number one cause of death in the world, and the size of the population at risk continues to increase rapidly. The dysregulation of the endocannabinoid (eCB) […]

Could cannabis liberalisation lead to wider changes in drug policies and outcomes?

Int J Drug Policy. 2017 Dec 8. pii: S0955-3959(17)30324-9. doi: 10.1016/j.drugpo.2017.10.004. [Epub ahead of print] Hughes B1, Wiessing L2, Des Jarlais D3, Griffiths P4. Author information Abstract Cannabis policies are changing in some countries. This may have consequences that extend beyond cannabis-specific outcomes, such as an impact on the consumption patterns of other substances. Changes […]

Associations between medical cannabis and other drug use among unstably housed women.

Int J Drug Policy. 2017 Dec 8;52:45-51. doi: 10.1016/j.drugpo.2017.11.009. [Epub ahead of print] Meacham MC1, Ramo DE2, Kral AH3, Riley ED4. Author information Abstract BACKGROUND: Several studies suggest that U.S. state-level legalization of cannabis for medical purposes may be associated with reductions in opioid use; yet its relationship with stimulant use, particularly in high-risk populations […]