Cannabinoid testing

Sir, I read with interest the recent correspondence by S. Antoniou entitled ‘Cannabinoids – high expectations?’¹

The author mentions that cannabinoids have been demonstrated to possess bactericidal efficacy on a par with chlorhexidine without its tooth discolouration effect. The study quoted, however, has not evaluated tooth discolouration, only the bacterial colony counts. In fact, cannabinoid products still need to be tested for their discolouration potential in comparison to chlorhexidine.²Additionally, not only do cannabinoids reduce bacterial colony counts but also increase the bactericidal efficiency of antibiotics against both gram-negative and gram-positive bacteria.²