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cannabinoid enthusiasts always welcome

Faces of Cannabis, Manitoba; Walter Leslie

Introducing a very green Canadian born in Vancouver, British Columbia; welder, Soapstone Carver, Winnipeg Jets fan, loveable family man blessed with 6 children, 22 grandkids and 3 great grandkids. This former Liberal Party delegate, who actively participated in Hemp legalization and the Global Days against the Drug War was involved in Winnipeg’s first ever planned 4/20 event, […]

Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model

Braz J Med Biol Res. 2018 Mar 15;51(5):e7132. doi: 10.1590/1414-431X20177132. Callejas GH1, Figueira RL1, Gonçalves FLL1, Volpe FAP1, Zuardi AW2, Crippa JA2, Hallak JE2, Sbragia L1. Author information Abstract Gastroschisis (GS) is an abdominal wall defect that results in histological and morphological changes leading to intestinal motility perturbation and impaired absorption of nutrients. Due to […]

Suppression of Cisplatin-Induced Vomiting by Cannabis sativa in Pigeons: Neurochemical Evidences.

Front Pharmacol. 2018 Mar 16;9:231. doi: 10.3389/fphar.2018.00231. eCollection 2018. Ullah I1,2, Subhan F2, Alam J2,3, Shahid M2, Ayaz M4. Author information Abstract Cannabis sativa (CS, family Cannabinaceae) has been reported for its anti-emetic activity against cancer chemotherapy-induced emesis in animal models and in clinics. The current study was designed to investigate CS for potential effectiveness […]

Faces of Cannabis, Manitoba; Scott Cook

Introducing original musician, painter and one of Manitoba’s faces of Cannabis; Scott Cook. This well rounded and original Canadian artist was born in Quebec. Growing up in a Royal Canadian Air Force family played a role in living in other provinces such as New Brunswick, Alberta, Ontario and good ol’ Nova Scotia. A true artist, Scott […]

Cannabis for paediatric epilepsy: challenges and conundrums.

Med J Aust. 2018 Feb 19;208(3):132-136. Chen KA1, Farrar MA2, Cardamone M2, Lawson JA2. Author information Abstract Research is expanding for the use of cannabidiol as an anticonvulsant drug. The mechanism of cannabidiol in paediatric epilepsy is unclear but is thought to play a role in modulation of synaptic transmission. Evidence for its efficacy in […]

Regulating Cannabis Manufacturing: Applying Public Health Best Practices from Tobacco Control.

J Psychoactive Drugs. 2018 Feb 13:1-14. doi: 10.1080/02791072.2017.1422816. [Epub ahead of print] Orenstein DG1, Glantz SA2. Author information Abstract State legalization and regulation of cannabis, despite continued federal illegality, is a massive shift in regulatory approach. Manufactured cannabis, including concentrates, extracts, edibles, tinctures, topicals and other products, has received less attention than more commonly used […]

Plasma N-acylethanolamine and endocannabinoid levels in burning mouth syndrome: potential role in disease pathogenesis.

J Oral Pathol Med. 2018 Feb 13. doi: 10.1111/jop.12692. [Epub ahead of print] Barry A1, O’Halloran KD1, McKenna JP2, McCreary C2, Harhen B3,4, Kerr DM3,4, Finn DP3,4, Downer EJ5. Author information Abstract OBJECTIVE: The objective was to measure endocannabinoid (eCB) ligands and non-cannabinoid N-acylethanolamine (NAE) molecules in plasma from individuals with burning mouth syndrome (BMS), […]

Ultrasound-Assisted Extraction of Cannabinoids from Cannabis Sativa L. Optimized by Response Surface Methodology.

J Food Sci. 2018 Feb 13. doi: 10.1111/1750-3841.14075. [Epub ahead of print] Agarwal C1, Máthé K2, Hofmann T3, Csóka L1. Author information Abstract Ultrasonication was used to extract bioactive compounds from Cannabis sativa L. such as polyphenols, flavonoids, and cannabinoids. The influence of 3 independent factors (time, input power, and methanol concentration) was evaluated on […]

Cannabis use is associated with lower rates of initiation of injection drug use among street-involved youth: A longitudinal analysis.

Drug Alcohol Rev. 2018 Feb 12. doi: 10.1111/dar.12667. [Epub ahead of print] Reddon H1,2, DeBeck K1,3, Socias ME1,4, Dong H1, Wood E1,4, Montaner J1,4, Kerr T1,4, Milloy MJ1,4. Author information Abstract INTRODUCTION AND AIMS: Street-involved youth are known to be at elevated risk of initiating injection drug use. However, the impact of so-called ‘gateway’ drugs, […]

Alterations in Gene and Protein Expression of Cannabinoid CB2 and GPR55 Receptors in the Dorsolateral Prefrontal Cortex of Suicide Victims.

Neurotherapeutics. 2018 Feb 12. doi: 10.1007/s13311-018-0610-y. [Epub ahead of print] García-Gutiérrez MS1,2, Navarrete F1,2, Navarro G3,4, Reyes-Resina I3,4, Franco R3,4, Lanciego JL4,5, Giner S6, Manzanares J7,8. Author information Abstract Recent studies point to the cannabinoid CB2 receptors (CB2r) and the non-cannabinoid receptor GPR55 as potential key targets involved in the response to stress, anxiety, and […]