Review
†Department of Chemical and Pharmaceutical Sciences and ‡Department of Medical Science, Pharmacology Section, University of Ferrara, Ferrara 44121, Italy
Chem. Rev., 2016, 116 (2), pp 519–560
DOI: 10.1021/acs.chemrev.5b00411
Publication Date (Web): January 07, 2016
Copyright © 2016 American Chemical Society
Biography
Mojgan Aghazadeh Tabrizi received her B.S. degree in Medicinal Chemistry and her Ph.D. degree in Pharmaceutical Sciences (1991) from Ferrara University, Italy. She has worked at the Department of Pharmaceutical Sciences of Ferrara University, focusing her interests on the design and synthesis of adenosine receptor ligands and antitumor compounds in collaboration with the company King Pharmaceuticals (North Carolina), now part of Pfizer. Since 2008, she has been part of a research project on the treatment of pain and inflammation involving the endocannabinoid system. She is author/coauthor of several scientific publications in the field of medicinal chemistry.
Biography
Pier Giovanni Baraldi received his degree in Chemistry in 1974 from the University of Ferrara, where he is currently Full Professor of Medicinal Chemistry. He has published more than 400 scientific papers including about 50 patents, focusing his research activity on the design and synthesis of DNA minor groove alkylating agents, combretastatin analogs, and ligands for ARs and TRP channel modulators. He has presented more than 90 lectures as speaker in international congresses. He was founder with Prof. Pier Andrea Borea of the spin off Pharmeste involved in the discovery of TRPV1 compounds
Biography
Pier Andrea Borea received his degree in Chemistry from the University of Ferrara in 1967. He is currently President of the Evaluation Board of the University of Ferrara. He has published 400 publications in international journals and contributed about 20 chapters to international books. He has participated in more than 200 congresses, presenting main, oral, and poster communications. He is also named as inventor in about 20 patents. He has been invited to give about 50 Plenary Lectures at International Symposia and at several universities. His main field of interest is represented by the study of drug–receptor interactions at the molecular level.
Biography
Katia Varani received her Doctoral degree in Biology in 1988 and her Ph.D. degree in Cellular and Molecular Pharmacology in 1995 from the University of Ferrara. She is currently Associate Professor of Pharmacology at the Medical Sciences Department of the University of Ferrara. She is author/coauthor of several scientific publications involving various topics such as the following: pharmacological, biochemical, and molecular study of adenosine receptors; interactions of G-protein-coupled receptors and human neurodegenerative diseases; chronic and neuropathic pain, cardiovascular disorders; inflammatory diseases and cancer.
