Canna~Fangled Abstracts Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signalling Deficiency. 2015 Jun 17. doi: 10.1038/npp.2015.173. Cristino L1, Luongo L2, Imperatore R1, Boccella S2, Becker T3, Morello G3, Piscitelli F1, Busetto G4, Maione S2, Di…Freedom WaresJune 17, 2015