Archive | September, 2004

The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L.

 2004 Sep 17;279(38):39767-74. Epub 2004 Jun 9. The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L. Sirikantaramas S1, Morimoto S, Shoyama Y, Ishikawa Y, Wada Y, Shoyama Y, Taura F. Author information Abstract Delta(1)-tetrahydrocannabinolic acid (THCA) synthase is the enzyme that catalyzes oxidative cyclization of cannabigerolic acid into THCA, the precursor of […]

Arachidonylethanolamide induces apoptosis of human glioma cells through vanilloid receptor-1.

Arachidonylethanolamide induces apoptosis of human glioma cells through vanilloid receptor-1. Contassot E, Wilmotte R, Tenan M, Belkouch MC, Schnüriger V, de Tribolet N, Burkhardt K, Dietrich PY. Author information Erratum in J Neuropathol Exp Neurol. 2004 Nov;63(11):1114. Bourkhardt, Karim [corrected to Burkhardt, Karim]. Abstract The anti-tumor properties of cannabinoids have recently been evidenced, mainly with delta9-tetrahydrocannabinol (THC). However, the clinical application of […]

The endocannabinoid system and its therapeutic exploitation.

2004 Sep;3(9):771-84. The endocannabinoid system and its therapeutic exploitation. Di Marzo V1, Bifulco M, De Petrocellis L. Author information  Abstract The term ‘endocannabinoid’ – originally coined in the mid-1990s after the discovery of membrane receptors for the psychoactive principle in Cannabis, Delta9-tetrahydrocannabinol and their endogenous ligands – now indicates a whole signalling system that comprises cannabinoid receptors, endogenous ligands and […]