Archive | January, 2005

Cannabinoids down-regulate PI3K/Akt and Erk signalling pathways and activate proapoptotic function of Bad protein.

 2005 Jan;17(1):25-37. Cannabinoids down-regulate PI3K/Akt and Erk signalling pathways and activate proapoptotic function of Bad protein. Ellert-Miklaszewska A1, Kaminska B, Konarska L. Author information Abstract Cannabinoids were shown to induce apoptosis of glioma cells in vitro and tumor regression in vivo, but mechanisms of their antiproliferative action remain elusive. In the present studies, C6 cells were exposed […]

Involvement of cannabinoids in cellular proliferation.

2005 Jan;5(1):97-106. Involvement of cannabinoids in cellular proliferation. López-Rodríguez ML1, Viso A, Ortega-Gutiérrez S, Díaz-Laviada I. Author information Abstract The endogenous canabinoid system (ECS) is involved in the regulation of an important number of central and peripheral physiological effects. Among all these functions, the control of the cellular proliferation has become a focus of major attention as opening newtherapeutic […]