Archive | July, 2009

CB2 Cannabinoid Receptors Contribute to Bacterial Invasion and Mortality in Polymicrobial Sepsis

PLoS One. 2009; 4(7): e6409. Published online Jul 29, 2009.doi:  10.1371/journal.pone.0006409 PMCID: PMC2712683 CB2 Cannabinoid Receptors Contribute to Bacterial Invasion and Mortality in Polymicrobial Sepsis Balázs Csóka,1 Zoltán H. Németh,1,2 Partha Mukhopadhyay,3 Zoltán Spolarics,1 Mohanraj Rajesh,3 Stephanie Federici,1 Edwin A. Deitch,1Sándor Bátkai,3 Pál Pacher,3,* and György Haskó1,* Neeraj Vij, Editor Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC.   Go to: Abstract […]

Cannabinoid system in the skin – a possible target for future therapies in dermatology.

Piotr Kupczyk,Adam Reich,Jacek C. Szepietowski First published: 24 July 2009Full publication history DOI: 10.1111/j.1600-0625.2009.00923.xView/save citation Cited by: 24 articles Citation tools  Prof. Jacek C. Szepietowski, MD, PhD, Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Ul. T. Chalubinskiego 1, 50-368 Wroclaw, Poland, Tel.: +48-71-7842288, Fax: +48-71-3270942, e-mail: jszepiet@derm.am.wroc.pl Abstract Previous article in issue: Skin and heart: une liaison dangereuse […]

Pursuing Paradoxical Proconvulsant Prophylaxis for Epileptogenesis

Epilepsia. Author manuscript; available in PMC Sep 15, 2010. Published in final edited form as: Epilepsia. Jul 2009; 50(7): 1657–1669. Published online Jul 1, 2009. doi:  10.1111/j.1528-1167.2009.02173.x PMCID: PMC2894282 NIHMSID: NIHMS175629 Pursuing Paradoxical Proconvulsant Prophylaxis for Epileptogenesis Caren Armstrong, Robert J. Morgan, and Ivan Soltesz Author information ► Copyright and License information ► The publisher’s final edited version of this article is available at Epilepsia […]

Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines.

2009 Jul;155(1):40-7. doi: 10.1016/j.jss.2008.06.045. Epub 2008 Aug 9. Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. Miyato H1, Kitayama J, Yamashita H, Souma D, Asakage M, Yamada J, Nagawa H. Author information Abstract Orally applicable Delta9-tetrahydrocannabinol and its synthetic derivatives have been used as antiemetic drugs during chemotherapy in cancerpatients. However, it is not well known how cannabinoids influence the effects […]

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma.

2009 Jul;8(7):1838-45. doi: 10.1158/1535-7163.MCT-08-1147. Epub 2009 Jun 9. Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma. Oesch S1, Walter D, Wachtel M, Pretre K, Salazar M, Guzmán M, Velasco G, Schäfer BW. Author information Abstract Gene expression profiling has revealed that the gene coding for cannabinoid receptor 1 (CB1) is highly up-regulated in rhabdomyosarcoma biopsies bearing the […]

Cannabinoid receptor ligands as potential anticancer agents–high hopes for new therapies?

 2009 Jul;61(7):839-53. doi: 10.1211/jpp/61.07.0002. Cannabinoid receptor ligands as potential–high hopes for new therapies? Oesch S1, Gertsch J. Author information Abstract OBJECTIVES: The endocannabinoid system is an endogenous lipid signalling network comprising arachidonic-acid-derived ligands, cannabinoid (CB) receptors, transporters and endocannabinoid degrading enzymes. The CB(1) receptor is predominantly expressed in neurons but is also co-expressed with the CB(2) […]