Archive | December, 2012

Isolation and characterization of some phytochemicals from Indian traditional plants.

Biotechnol Res Int. 2012; 2012: 549850. Published online 2012 December 11. doi:  10.1155/2012/549850 PMCID: PMC3529893 Isolation and Characterization of Some Phytochemicals from Indian Traditional Plants Neeharika Srivastava, Aishwarya Singh Chauhan, and Bechan Sharma* Author information ► Article notes ► Copyright and License information ► Go to: Abstract The present study was designed to evaluate relative contribution of different polyphenols (total phenolics, flavonoids, flavonols) and their antioxidants activities […]

The evolution and comparative neurobiology of endocannabinoid signalling

Philos Trans R Soc Lond B Biol Sci. 2012 December 5; 367(1607): 3201–3215. doi:  10.1098/rstb.2011.0394 PMCID: PMC3481536 The evolution and comparative neurobiology of endocannabinoid signalling Maurice R. Elphick* Author information ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: ABSTRACT CB1- and CB2-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in […]

What place for ▾ cannabis extract in MS?

2012 Dec;50(12):141-4. doi: 10.1136/dtb.2012.11.0150. What place for ▾ cannabis extract in MS? [No authors listed] Abstract Multiple sclerosis (MS) is a neurological condition that is estimated to affect around 60,000 people in England and Wales, with a lifetime risk in the UK of 1 in 1,000.(1,2) Spasticity (an increase in muscle tone) is a common symptom of […]

Why do cannabinoid receptors have more than one endogenous ligand?

Philos Trans R Soc Lond B Biol Sci. Dec 5, 2012; 367(1607): 3216–3228. doi:  10.1098/rstb.2011.0382 PMCID: PMC3481524 Why do cannabinoid receptors have more than one endogenous ligand? Vincenzo Di Marzo1,* and Luciano De Petrocellis2 Author information ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: ABSTRACT The endocannabinoid system was revealed following the understanding of […]

Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities.

Philos Trans R Soc Lond B Biol Sci. Dec 5, 2012; 367(1607): 3353–3363.  doi:  10.1098/rstb.2011.0381 PMCID: PMC3481523 Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities Roger G. Pertwee* Author information ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: ABSTRACT Human tissues express cannabinoid CB1 and CB2 receptors that can […]