Archive | June, 2014

Medical marijuana: A panacea or scourge

Lung India. 2014 Apr-Jun; 31(2): 145–148.  doi:  10.4103/0970-2113.129843 PMCID: PMC3999675 Medical marijuana: A panacea or scourge Surender Kashyap and  Kartikeya Kashyap1 Author information ► Copyright and License information ► Go to: Abstract Marijuana (Cannabis sativa) has been used for recreational and medical purposes since ages. Marijuana smoking is an evil, which is on the rise with about 180.6 million active users worldwide. […]

The rotation of white lupin (Lupinus albus L.) with metal-accumulating plant crops: A strategy to increase the benefits of soil phytoremediation.

2014 Jun 30;145C:35-42. doi: 10.1016/j.jenvman.2014.06.001. [Epub ahead of print] The rotation of white lupin (Lupinus albus L.) with metal-accumulating plant crops: A strategy to increase the benefits of soil phytoremediation. Fumagalli P1, Comolli R2, Ferrè C3, Ghiani A4, Gentili R5, Citterio S6. Author information Abstract Most of the plants employed to remove metals from contaminated soils are annuals and have […]

Clinical endocannabinoid deficiency (CECD) revisited: Can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

2014 Jun 30;35(3):198-201. [Epub ahead of print] Clinical endocannabinoid deficiency (CECD) revisited: Can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? Smith SC, Wagner MS. Author information Abstract OBJECTIVES: Ethan B. Russo’s paper of December 1, 2003 explored the concept of a clinical endocannabinoid deficiency (CECD) […]

Alzheimer’s, Cancer and Homeostatic Cannabinoid Science

  Alzheimer’s, Cancer and Homeostatic Cannabinoid Science 06/29/14 The Cannabis Papers by Publius (2011) The Cannabis Papers: A citizen’s guide to cannabinoids (2011) By Publius  The CS World Cup: Goaltender Edition Today, tending to the goals of mediating Alzheimer’s and preventing carcinogenesis, Publius spotlights two June abstracts from PubMed on the homeostatic cannabinoid system (CS). […]

Neuroimaging in Huntington’s disease

World J Radiol. Jun 28, 2014; 6(6): 301–312.  Published online Jun 28, 2014. doi:  10.4329/wjr.v6.i6.301 PMCID: PMC4072816 Neuroimaging in Huntington’s disease Flavia Niccolini and  Marios Politis Author information ► Article notes ► Copyright and License information ► Go to: Abstract Huntington’s disease (HD) is a progressive and fatal neurodegenerative disorder caused by an expanded trinucleotide CAG sequence in huntingtin gene (HTT) on chromosome 4. HD […]

Safety and pharmacokinetics of oral delta-9-tetrahydrocannabinol in healthy older subjects: A randomized controlled trial.

 2014 Jun 28. pii: S0924-977X(14)00175-8. doi: 10.1016/j.euroneuro.2014.06.007. [Epub ahead of print] Safety and pharmacokinetics of oral delta-9-tetrahydrocannabinol in healthy older subjects: A randomized controlled trial. Ahmed AI1, van den Elsen GA2, Colbers A3, van der Marck MA2, Burger DM3, Feuth TB4, Rikkert MG2, Kramers C5. Author information Abstract There is a great concern about the safety of THC-based drugs in older people […]

Detection of cannabinoid receptors CB1 and CB2 within basal ganglia output neurons in macaques: changes following experimental parkinsonism.

2014 Jun 28. [Epub ahead of print] Detection of cannabinoid receptors CB1 and CB2 within basal ganglia output neurons in macaques: changes following experimental parkinsonism. Sierra S1, Luquin N, Rico AJ, Gómez-Bautista V, Roda E, Dopeso-Reyes IG, Vázquez A, Martínez-Pinilla E,Labandeira-García JL, Franco R, Lanciego JL. Author information Abstract Although type 1 cannabinoid receptors (CB1Rs) are expressed abundantly throughout the brain, the presence of type 2 cannabinoid receptors (CB2Rs) in […]

The cannabis conundrum (Richard J. Miller)

Proc Natl Acad Sci U S A. Oct 22, 2013; 110(43): 17165. Published online Oct 22, 2013. doi:  10.1073/pnas.1317663110 PMCID: PMC3808660 The cannabis conundrum Richard J. Miller1 Author information ► Copyright and License information ► Richard Miller. The debate about cannabis (also known as marijuana or Indian hemp) continues. Is it “dangerous”? Is it “addictive”? Does it make you “crazy”? Everybody […]

The influence of endocannabinoid receptor 1 gene variations on anthropometric and metabolic parameters of women with polycystic ovary syndrome.

2014;65(3):181-188. doi: 10.5603/EP.2014.0025. The influence of endocannabinoid receptor 1 gene variations on anthropometric and metabolic parameters of women with polycystic ovary syndrome. Lenarcik-Kabza A1, Laczmański L, Milewicz A, Bidzińska-Speichert B, Pawlak M, Kolackov K, Kuliczkowska-Płaksej J, Trzmiel-Bira A, Brona A. Author information Abstract INTRODUCTION: Polycystic ovary syndrome (PCOS) is associated with an increasing number of metabolic comorbidities. About 50% of PCOS patients are obese, and […]

JWH-018 in rhesus monkeys: Differential antagonism of discriminative stimulus, rate-decreasing, and hypothermic effects.

2014 Jun 24. pii: S0014-2999(14)00465-8. doi: 10.1016/j.ejphar.2014.06.023. [Epub ahead of print] JWH-018 in rhesus monkeys: Differential antagonism of discriminative stimulus, rate-decreasing, and hypothermic effects. Rodriguez JS1, McMahon LR2. Author information Abstract Several effects of the abused synthetic cannabinoid JWH-018 were compared to those of Δ9-tetrahydrocannabinol (Δ9-THC) in rhesus monkeys. JWH-018 (0.1mg/kg i.v.) was established as a discriminative stimulus […]