Archive | April, 2005

Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood.

2005 Apr;230(4):225-34. Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. Fride E, Bregman T, Kirkham TC. Author information Abstract The appetite-stimulating effects of the cannabis plant (Cannabis sativa) have been known since ancient times, and appear to be effected through the incentive and rewarding properties of foods. Investigations into the biological basis of the multiple effects of cannabis have […]


Cannabinoids as Therapeutics

BirkhäuserBirkhäuser BioSciences Milestones in Drug Therapy Free Preview © 2005 Editors: Mechoulam, Raphael (Ed.) About this book       In recent years, cannabis research has concentrated on the potential of cannabinoids as therapeutic substances, particularly in serious chronic illnesses such as multiple sclerosis. Most volumes published on cannabinoids so far concentrate on the biological […]

The phylogenetic distribution and evolutionary origins of endocannabinoid signalling.

2005;(168):283-97. The phylogenetic distribution and evolutionary origins of endocannabinoid signalling. Elphick MR1, Egertová M. Author information Abstract The endocannabinoid signalling system in mammals comprises several molecular components, including cannabinoid receptors (e.g. CB1, CB2), putative endogenous ligands for these receptors [e.g. anandamide, 2-arachidonoylglycerol (2-AG)] and enzymes involved in the biosynthesis and inactivation of anandamide (e.g. NAPE-PLD, FAAH) and 2-AG (e.g. DAG lipase, MGL). In this review we […]

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Protective effects of Δ9-tetrahydrocannabinol against N-methyl-D-aspartate-induced AF5 cell death

Brain Res Mol Brain Res. Author manuscript; available in PMC 2007 Mar 15. Published in final edited form as: Brain Res Mol Brain Res. 2005 Apr 4; 134(2): 215–225.  doi:  10.1016/j.molbrainres.2004.10.044 PMCID: PMC1824211 NIHMSID: NIHMS16448 Protective effects of Δ9-tetrahydrocannabinol against N-methyl-D-aspartate-induced AF5 cell death Jia Chen,a,* Chun-Ting Lee,a Stacie Errico,a Xiaolin Deng,b Jean L. Cadet,b and  William J. Freeda Author information ► Copyright and License information ► The […]