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Enantioselective Total Synthesis of Cannabinoids-A Route for Analogue Development.

By Freedom WaresJanuary 2, 2018No Comments

Home » Enantioselective Total Synthesis of Cannabinoids-A Route for Analogue Development.

Org Lett. 2018 Jan 2. doi: 10.1021/acs.orglett.7b03668.

[Epub ahead of print]

Shultz ZP¹, Lawrence GA¹, Jacobson JM¹, Cruz EJ¹, Leahy JW^1,^2,³.

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Abstract

A practical synthetic approach to Δ⁹-tetrahydrocannabinol (1) and cannabidiol (2) that provides scalable access to these natural products and should enable the generation of novel synthetic analogues is reported.

PMID: 29293352
DOI: 10.1021/acs.orglett.7b03668

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Enantioselective Total Synthesis of Cannabinoids-A Route for Analogue Development.

Author information

Abstract

Freedom Wares

Previous PostAcute and chronic modulation of striatal endocannabinoid-mediated plasticity by nicotine.

Next PostInsights into the molecular regulation of monolignol-derived product biosynthesis in the growing hemp hypocotyl.