Int J Med Sci. 2018 Aug 6;15(12):1286-1295. doi: 10.7150/ijms.27087. eCollection 2018.
Papaseit E1,2, Pérez-Mañá C1,2, Pérez-Acevedo AP1,2, Hladun O1,2, Torres-Moreno MC1,2, Muga R2,3, Torrens M2,4, Farré M1,2.
Abstract
Cannabis is becoming increasingly present in our society. In recent years, the line between the natural (cannabis) and the synthetic (synthetic cannabinoids), the recreational (cannabis) and the medical (pharmaceutical cannabinoids and medical cannabis) has been crossed. In this paper we review some of the novel aspects of cannabis and cannabinoids in relation to their legal situation, changes in their composition and forms of cannabis use, the concept of medical cannabis, and synthetic cannabinoids as new psychoactive substances (NPS). We have also analyzed serious adverse reactions and intoxications associated with the use of synthetic cannabinoids, as well as the latest developments in the research of pharmaceutical cannabinoids.
KEYWORDS:
Cannabis, Delta-9-tetrahydrocannabinol (THC), Cannabidiol (CBD), Medical cannabis; Synthetic cannabinoid
- PMID: 30275754
- PMCID: PMC6158663
- DOI: 10.7150/ijms.27087
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Conflict of interest statement
Competing Interests: The authors have declared that no competing interest exists.