2014 May 21. doi: 10.1111/jcpt.12179. [Epub ahead of print]

Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson’s disease patients: a case series.

Chagas MH1, Eckeli AL, Zuardi AW, Penna-Pereira MA, Sobreira-Neto MA, Sobreira ET, Camilo MR, Bergamaschi MM, Schenck CH, Hallak JE, Tumas V, Crippa JA.

Author information

Abstract

WHAT IS KNOWN AND OBJECTIVE:

Cannabidiol (CBD) is the main non-psychotropic component of the Cannabis sativa plant. REM sleep behaviour disorder (RBD) is a parasomnia characterized by the loss of muscle atonia during REM sleep associated with nightmares and active behaviour during dreaming. We have described the effects of CBD in RBD symptoms in patients with Parkinson’s disease.

CASES SUMMARY:

Four patients treated with CBD had prompt and substantial reduction in the frequency of RBD-related events without side effects.

WHAT IS NEW AND CONCLUSION:

KEYWORDS:

Parkinson’s disease, cannabidiol, rapid eye movement sleep behaviour disorder

PMID:: 24845114; [PubMed – as supplied by publisher]

Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson's disease patients: a case series.