In Vivo imaging of the cannabinoid CB1 receptor with positron emission tomography.

Positron emission tomography (PET) can visualize and quantify receptors and other targets in the living human brain, and recent progress in radioligand development has enabled measurement of cannabinoid CB1 receptors. Cannabinoid CB1 receptors have been implicated in multiple human diseases, such as obesity, mood disorders, and addiction. First in vivo human studies have shown distinctive spatial and temporal alterations in cannabinoid CB1 receptor binding in addictive disorders. This article is protected by copyright. All rights reserved.
© 2015 American Society for Clinical Pharmacology and Therapeutics.