Neuropathic pain affects millions of people over the world each year. It is a severe public health problem produced by post-traumatic and post-surgical nerve injury, disease states as well as toxic insults. Pain-associated syndromes (shooting pain, burning pain, dysesthesia and paresthesia) as well as sensory abnormalities and neuroma due to neuropathy can largely influence the patient’s daily life.¹ Indeed, patients who are suffering from neuropathic pain are still under-diagnosed and under-treated. Although medications (such as opioids, antidepressants, anticonvulsants and cannabinoids) are used to manage neuropathic pain clinically, effective and safe treatments for neuropathic pain are still missing.² Identification of novel analgesics that are efficacious and lack central side effects in both preclinical and clinical studies is needed. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.

PMID:

 23701118
[PubMed – as supplied by publisher]