Canna~Fangled Abstracts

Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors.

By November 29, 2013 No Comments

pm8Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors.

Source

Laboratory for Radiopharmacy, IMIR KU Leuven, O&N2, Herestraat 49, Box 821, BE-3000, Leuven, Belgium.

Abstract

Despite its abundant expression in the brain, the cannabinoid type-1 (CB1) receptor was discovered only in 1988. During the last decade, efforts from several research groups have made it possible to visualize the CB1 receptor in vivo to unravel its role in the brain physiology and pathology. This review discusses strategies for (radio)synthesis of radioligands for in vivo imaging of CB1 receptors.
Copyright © 2013 John Wiley & Sons, Ltd.

KEYWORDS:

CB1 receptors, in vivo imaging, positron emission tomography, radiosynthesis

PMID:

 

24285327

 

[PubMed – in process]
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