Canna~Fangled Abstracts The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity Neuropharmacology. 2021 Jan 12;108450. doi: 10.1016/j.neuropharm.2021.108450. Online ahead of print. Despina Kokona 1, Dimitris Spyridakos 2, Manolis Tzatzarakis 3, Sofia Papadogkonaki 4, Eirini…Freedom WaresJanuary 12, 2021
Canna~Fangled Abstracts Endocannabinoid metabolism and transport as targets to regulate intraocular pressure Exp Eye Res. 2020 Sep 23;108266. doi: 10.1016/j.exer.2020.108266. Online ahead of print. Sally Miller 1, Laura Daily 1, Vijai…Freedom WaresSeptember 23, 2020
Canna~Fangled Abstracts ABHD6: Its Place in Endocannabinoid Signaling and Beyond. Trends Pharmacol Sci. 2019 Mar 7. pii: S0165-6147(19)30033-1. doi: 10.1016/j.tips.2019.02.002. Cao JK1, Kaplan J1, Stella…Freedom WaresMarch 7, 2019
Canna~Fangled Abstracts Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination. Biochem Pharmacol. 2018 Jul 31. pii: S0006-2952(18)30311-3. doi: 10.1016/j.bcp.2018.07.042. Manterola A1, Bernal-Chico A1, Cipriani R1,…Freedom WaresAugust 5, 2018
Canna~Fangled Abstracts Monoacylglycerol signalling and ABHD6 in health and disease. Diabetes Obes Metab. 2017 Sep;19 Suppl 1:76-89. doi: 10.1111/dom.13008. Poursharifi P1, Madiraju SRM1, Prentki M1.…Freedom WaresSeptember 8, 2017
Canna~Fangled Abstracts Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors. 2014 Dec 11. doi: 10.1002/cmdc.201402453. Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors.…Freedom WaresDecember 11, 2014
Canna~Fangled Abstracts ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice. 2014 Jul 16;83(2):361-371. doi: 10.1016/j.neuron.2014.06.030. ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in…Freedom WaresJuly 16, 2014
Canna~Fangled Abstracts In vivo metabolite profiling as a means to identify uncharacterized lipase function: Recent success stories within the alpha beta hydrolase domain (ABHD) enzyme family. 2014 Jan 11. pii: S1388-1981(14)00009-2. doi: 10.1016/j.bbalip.2014.01.004. In vivo metabolite profiling as a means to…Freedom WaresJanuary 11, 2014
Canna~Fangled Abstracts The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors PMC3320662 Acta Physiologica (Oxford, England) Wiley-Blackwell, John Wiley & Sons Acta Physiol (Oxf). 2012 February; 204(2): 267–276.…Freedom WaresOctober 9, 2013