Archive by Author

Endophytes of industrial hemp (Cannabis sativa L.) cultivars: identification of culturable bacteria and fungi in leaves, petioles, and seeds.

Can J Microbiol. 2018 Jun 18:1-17. doi: 10.1139/cjm-2018-0108. [Epub ahead of print] Scott M1,1, Rani M1,1, Samsatly J1,1, Charron JB1,1, Jabaji S1,1. Author information Abstract Plant endophytes are a group of microorganisms that reside asymptomatically within the healthy living tissue. The diversity and molecular and biochemical characterization of industrial hemp-associated endophytes have not been previously […]

Effects of Δ9-THC and cannabidiol vapor inhalation in male and female rats.

Psychopharmacology (Berl). 2018 Jun 16. doi: 10.1007/s00213-018-4946-0. [Epub ahead of print] Javadi-Paydar M1, Nguyen JD1, Kerr TM1, Grant Y1, Vandewater SA1, Cole M2, Taffe MA3. Author information Abstract RATIONALE: Previous studies report sex differences in some, but not all, responses to cannabinoids in rats. The majority of studies use parenteral injection; however, most human use […]

Is Cannabis Use Treatment Also Indicated for Patients with Low to Moderate Polysubstance Use.

Eur Addict Res. 2018 Jun 14;24(2):79-87. doi: 10.1159/000488345. [Epub ahead of print] Neumann M1, Bühringer G1,2, Höfler M1, Wittchen HU1,3, Hoch E3. Author information Abstract BACKGROUND: Polysubstance use (PSU) is common among patients with cannabis use (CU) and is related to more severe CU problems. However, it is unclear how PSU predicts CU treatment outcomes […]

Religious Involvement and Marijuana Use for Medical and Recreational Purposes.

J Drug Issues. 2018 Jul;48(3):421-434. doi: 10.1177/0022042618770393. Epub 2018 Apr 21. Burdette AM1, Webb NS1, Hill TD2, Haynes SH3, Ford JA4. Author information Abstract In this article, we use data from the 2016 National Survey on Drug Use and Health (NSDUH) to examine the association between religious involvement and marijuana use for medical and recreational […]

Endocannabinoid receptor CB2R is significantly expressed in aspirin-exacerbated respiratory disease: a pilot study.

Int Forum Allergy Rhinol. 2018 Jun 13. doi: 10.1002/alr.22163. [Epub ahead of print] Corrado A1, Battle M2, Wise SK2, Lee FE1, Guidot DM1, DelGaudio JM2, Molina SA1, Levy JM2. Author information Abstract BACKGROUND: The endocannabinoid system represents a highly conserved, innate signaling network with direct and indirect control of eicosanoid-mediated inflammation. Activation of the type […]

The impact of Cannabidiol treatment on regulatory T-17 Cells and neutrophil polarization in Acute Kidney Injury.

Am J Physiol Renal Physiol. 2018 Jun 13. doi: 10.1152/ajprenal.00112.2018. [Epub ahead of print] Baban B1, Hoda MN2, Malik A3, Khodadadi H3, Simmerman E, Vaibhav K4, Mozaffari MS3. Author information Abstract Hallmark features of acute kidney injury (AKI) include mobilization of immune and inflammatory mechanisms culminating in tissue injury. Emerging information indicates heterogeneity of neutrophils […]

Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis.

Br J Pharmacol. 2018 Jun 11. doi: 10.1111/bph.14387. [Epub ahead of print] Hill JD1,2, Zuluaga-Ramirez V1, Gajghate S1, Winfield M1, Persidsky Y1,2. Author information Abstract BACKGROUND AND PURPOSE: The cannabinoid system exerts functional regulation of neural stem cell (NSC) proliferation and adult neurogenesis, yet not all effects of cannabinoid-like compounds seen can be attributed to […]

Probing the endocannabinoid system in healthy volunteers: Cannabidiol alters fronto-striatal resting-state connectivity.

Eur Neuropsychopharmacol. 2018 Jun 7. pii: S0924-977X(18)30113-5. doi: 10.1016/j.euroneuro.2018.04.004. [Epub ahead of print] Grimm O1, Löffler M2, Kamping S3, Hartmann A2, Rohleder C4, Leweke M4, Flor H2. Author information Abstract Tetrahydrocannabinol (THC) and Cannabidiol (CBD) are two substances from cannabis sativa that have been implicated in the treatment of mental and neurological disorders. We concentrated […]

Cannabidiol did not induce teratogenicity or neurotoxicity in exposed zebrafish embryos.

Chem Biol Interact. 2018 Jun 11. pii: S0009-2797(18)30216-3. doi: 10.1016/j.cbi.2018.06.008. [Epub ahead of print] Valim Brigante TA1, Abe FR2, Zuardi AW3, Hallak JEC3, Crippa JAS3, de Oliveira DP4. Author information Abstract Cannabidiol (CBD) is a non-psychotomimetic compound of the Cannabis sativa that has been used for the treatment of severe epilepsy as well as other […]

Sub-chronic treatment with cannabidiol but not with URB597 induced a mild antidepressant-like effect in diabetic rats.

Neurosci Lett. 2018 Jun 6. pii: S0304-3940(18)30409-9. doi: 10.1016/j.neulet.2018.06.006. [Epub ahead of print] de Morais H1, Chaves YC1, Waltrick APF1, Jesus CHA1, Genaro K2, Crippa JA2, da Cunha JM1, Zanoveli JM3. Author information Abstract Depression associated with diabetes has been described as a highly debilitating comorbidity. Due to its complex and multifactorial mechanisms, the treatment […]