Canna~Fangled Abstracts CB 1 allosteric modulators and their therapeutic potential in CNS disorders Review Prog Neuropsychopharmacol Biol Psychiatry. 2020 Nov 2;110163. doi: 10.1016/j.pnpbp.2020.110163. Online ahead of print. Catharine…Freedom WaresNovember 2, 2020
Canna~Fangled Abstracts Signaling molecules targeting cannabinoid receptors: Hemopressin and related peptides. Neuropeptides. 2019 Nov 22:101998. doi: 10.1016/j.npep.2019.101998. Wei F1, Zhao L2, Jing Y3. Author information Abstract…Freedom WaresNovember 22, 2019
Canna~Fangled Abstracts Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington’s disease in the R6/2 mouse model. Neuropharmacology. 2019 Mar 30. pii: S0028-3908(19)30113-3. doi: 10.1016/j.neuropharm.2019.03.033. Laprairie RB1, Bagher AM2, Rourke JL3, Zrein…Freedom WaresMarch 30, 2019
Canna~Fangled Abstracts Translational potential of allosteric modulators targeting the cannabinoid CB1 receptor. Acta Pharmacol Sin. 2018 Oct 17. doi: 10.1038/s41401-018-0164-x. Lu D1, Immadi SS2, Wu Z2, Kendall…Freedom WaresOctober 17, 2018
Canna~Fangled Abstracts The future of type 1 cannabinoid receptor allosteric ligands. Drug Metab Rev. 2018 Jan 21:1-12. doi: 10.1080/03602532.2018.1428341. Alaverdashvili M1, Laprairie RB1. Author information Abstract…Freedom WaresJanuary 21, 2018
Canna~Fangled Abstracts The In Vivo Effects of the CB1-Positive Allosteric Modulator GAT229 on Intraocular Pressure in Ocular Normotensive and Hypertensive Mice. J Ocul Pharmacol Ther. 2017 Jul 18. doi: 10.1089/jop.2017.0037. Cairns EA1, Szczesniak AM1, Straiker AJ2,…Freedom WaresJuly 18, 2017
Canna~Fangled Abstracts Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. 2017 May 17. pii: S0028-3908(17)30230-7. doi: 10.1016/j.neuropharm.2017.05.018. Khurana L1, Mackie K2, Piomelli D3, Kendall…Freedom WaresMay 17, 2017
Canna~Fangled Abstracts Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as a discovery target. 2016 Oct 7. Janero DR1, Thakur GA2. Author information Abstract INTRODUCTION: Allosteric modulators of G-protein coupled…Freedom WaresOctober 7, 2016
Canna~Fangled Abstracts Cannabinoid receptor type-1: breaking the dogmas. 2016 May 24;5. pii: F1000 Faculty Rev-990. doi: 10.12688/f1000research.8245.1. eCollection 2016. Busquets Garcia A1, Soria-Gomez E1, Bellocchio…Freedom WaresMay 24, 2016
Canna~Fangled Abstracts Cannabidiol is a negative allosteric modulator of the type 1 cannabinoid receptor. 2015 Jul 27. doi: 10.1111/bph.13250. Laprairie RB1, Bagher AM1, Kelly ME1,2, Denovan-Wright EM1. Author information Abstract BACKGROUND AND…Freedom WaresJuly 27, 2015