Canna~Fangled Abstracts Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity Neuron. 2023 Feb 10;S0896-6273(23)00066-1. doi: 10.1016/j.neuron.2023.01.018. Online ahead of print. Evan C Rosenberg 1, Simon Chamberland 1, Michael Bazelot 2, Erica…Freedom WaresFebruary 10, 2023
Canna~Fangled Abstracts A Critical Evaluation of Terpenoid Signaling at Cannabinoid CB1 Receptors in a Neuronal Model Molecules. 2022 Sep 2;27(17):5655. doi: 10.3390/molecules27175655. Michaela Dvorakova 1, Sierra Wilson 1, Wesley Corey 1, Jenna Billingsley 1, Anaëlle Zimmowitch 1, Joye Tracey 1, Alex Straiker 1, Ken Mackie 1…Freedom WaresSeptember 2, 2022
Canna~Fangled Abstracts Endocannabinoid signaling in glioma Glia. 2022 Mar 24. doi: 10.1002/glia.24173. Online ahead of print. Carlos Costas-Insua 1 2 3, Manuel Guzmán 1 2 3 Affiliations expand PMID: 35322459…Freedom WaresMarch 24, 2022
Canna~Fangled Abstracts Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis Eur J Med Chem. 2021 Oct 5;226:113878. doi: 10.1016/j.ejmech.2021.113878. Online ahead of print. Wenwen Duan 1, Ying…Freedom WaresOctober 5, 2021
Canna~Fangled Abstracts Cannabinoid receptor type 2 ligands: an analysis of granted patents since 2010 Pharm Pat Anal. 2021 May;10(3):111-163. doi: 10.4155/ppa-2021-0002. Epub 2021 Jun 11. Benjamin Brennecke 1, Thais Gazzi 1, Kenneth Atz 2, Jürgen Fingerle 2, Pascal…Freedom WaresMay 10, 2021
Canna~Fangled Abstracts “Photo-Rimonabant”: Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar ” Cis-On” CB 1 R Antagonist ACS Chem Neurosci. 2021 Apr 15. doi: 10.1021/acschemneuro.1c00086. Online ahead of print. Diego A Rodríguez-Soacha 1, Julia…Freedom WaresApril 15, 2021
Canna~Fangled Abstracts Structural and Functional Insights into Cannabinoid Receptors Review Trends Pharmacol Sci. 2020 Jul 29;S0165-6147(20)30146-2. doi: 10.1016/j.tips.2020.06.010. Online ahead of print. Xiaoting Li 1, Ling…Freedom WaresJuly 29, 2020
Canna~Fangled Abstracts Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18 ACS Med Chem Lett. 2020 Jun 17;11(10):2024-2031. doi: 10.1021/acsmedchemlett.0c00208. eCollection 2020 Oct 8. Clara T Schoeder 1 2, Andhika…Freedom WaresJune 16, 2020
Canna~Fangled Abstracts GPR6 Structural Insights: Homology Model Construction and Docking Studies. Molecules. 2020 Feb 7;25(3). pii: E725. doi: 10.3390/molecules25030725. Isawi IH1, Morales P2, Sotudeh N3, Hurst…Freedom WaresFebruary 7, 2020
Canna~Fangled Abstracts Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures. Cell. 2020 Jan 28. pii: S0092-8674(20)30055-6. doi: 10.1016/j.cell.2020.01.008. Hua T1, Li X2, Wu L2, Iliopoulos-Tsoutsouvas…Freedom WaresJanuary 28, 2020