Canna~Fangled Abstracts Potent, Selective Agonists for the Cannabinoid-like Orphan G Protein-Coupled Receptor GPR18: A Promising Drug Target for Cancer and Immunity J Med Chem. 2024 Jun 17. doi: 10.1021/acs.jmedchem.3c02423. Online ahead of print. Andhika B Mahardhika 1 2 3, Michal…Freedom WaresJune 16, 2024
Canna~Fangled Abstracts The Interaction of the Endocannabinoid Anandamide and Paracannabinoid Lysophosphatidylinositol during Cell Death Induction in Human Breast Cancer Cells Journal List Int J Mol Sci PMC10888638 As a library, NLM provides access to scientific…Freedom WaresFebruary 14, 2024
Canna~Fangled Abstracts The Mechanisms of GPR55 Receptor Functional Selectivity during Apoptosis and Proliferation Regulation in Cancer Cells Journal List Int J Mol Sci PMC10054013 Int J Mol Sci. 2023 Mar; 24(6): 5524. Published…Freedom WaresMarch 24, 2023
Canna~Fangled Abstracts [GPR18 receptor – the structure and the role in the physiology and pathophysiology] Postepy Biochem. 2022 May 24;68(2):161-168. doi: 10.18388/pb.2021_399. Print 2022 Jun 30. Michalina Jurkiewicz 1, Greta Steć 2, Adrian Szczepaniak 3, Jakub Fichna 4, Marta…Freedom WaresJune 30, 2022
Canna~Fangled Abstracts THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner Previous studies have demonstrated anti-tumorigenic effects of THC and CBD in several tumor entities including…Freedom WaresMarch 3, 2021
Canna~Fangled Abstracts Therapeutic Exploitation of GPR18: Beyond the Cannabinoids? J Med Chem. 2020 Sep 11. doi: 10.1021/acs.jmedchem.0c00926. Online ahead of print. Paula Morales, Ana Lago-Fernandez, Dow…Freedom WaresSeptember 11, 2020
Canna~Fangled Abstracts The Role of Atypical Cannabinoid Ligands O-1602 and O-1918 on Skeletal Muscle Homeostasis with a Focus on Obesity Int J Mol Sci. 2020 Aug 18;21(16):E5922. doi: 10.3390/ijms21165922. Anna C Simcocks 1, Lannie O'Keefe 1 2, Kayte A Jenkin 1 3, Lauren…Freedom WaresAugust 18, 2020
Canna~Fangled Abstracts Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18 ACS Med Chem Lett. 2020 Jun 17;11(10):2024-2031. doi: 10.1021/acsmedchemlett.0c00208. eCollection 2020 Oct 8. Clara T Schoeder 1 2, Andhika…Freedom WaresJune 16, 2020
Canna~Fangled Abstracts Activation of CB1R Promotes Lipopolysaccharide-Induced IL-10 Secretion by Monocytic Myeloid-Derived Suppressive Cells and Reduces Acute Inflammation and Organ Injury. J Immunol. 2020 May 8. pii: ji2000213. doi: 10.4049/jimmunol.2000213. Joffre J1, Yeh CC1, Wong E2,…Freedom WaresMay 8, 2020
Canna~Fangled Abstracts Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity. Int J Mol Sci. 2019 May 9;20(9). pii: E2300. doi: 10.3390/ijms20092300. Sotudeh N1, Morales P2,…Freedom WaresMay 9, 2019