Canna~Fangled Abstracts An Unexpected Activity of a Minor Cannabinoid: Cannabicyclol (CBL) Is a Potent Positive Allosteric Modulator of Serotonin 5-HT1A Receptor J Nat Prod. 2025 Jan 15. doi: 10.1021/acs.jnatprod.4c00977. Online ahead of print. Mehdi Haghdoost 1, Yvonne DePorre 2, Max…Freedom WaresJanuary 15, 2025
Canna~Fangled Abstracts Assessing dose and sex dependent antinociceptive effects of cannabidiol and amitriptyline, alone and in combination, and exploring mechanism of action involving serotonin 1A receptors J Pharmacol Exp Ther. 2023 Dec 21:JPET-AR-2023-001855. doi: 10.1124/jpet.123.001855. Online ahead of print. Robert C…Freedom WaresDecember 21, 2023
Canna~Fangled Abstracts Role of 5HT1A Receptors in the Neuroprotective and Behavioral Effects of Cannabidiol in Hypoxic–Ischemic Newborn Piglets Journal List > Front Pharmacol > PMC9341521 Front Pharmacol. 2022; 13: 925740. Published online 2022 Jul…Freedom WaresJuly 18, 2022
Canna~Fangled Abstracts The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome. Eur J Pharmacol. 2018 Aug 16. pii: S0014-2999(18)30473-4. doi: 10.1016/j.ejphar.2018.08.016. Salaga M1, Binienda A1, Tichkule…Freedom WaresAugust 16, 2018
Canna~Fangled Abstracts RGS proteins as targets in the treatment of intestinal inflammation and visceral pain: New insights and future perspectives. 2016 Jan 28. doi: 10.1002/bies.201500118. Salaga M1, Storr M2, Martemyanov KA3, Fichna J1. Author information Abstract Regulators of…Freedom WaresJanuary 28, 2016
Canna~Fangled Abstracts Endocannabinoids blunt the augmentation of synaptic transmission by serotonin 2A receptors in the nucleus tractus solitarii (nTS). Endocannabinoids blunt the augmentation of synaptic transmission by serotonin 2A receptors in the nucleus tractus…Freedom WaresSeptember 18, 2013