Archive | February, 2018
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Prospective analysis of safety and efficacy of medical cannabis in large unselected population of patients with cancer.

Eur J Intern Med. 2018 Mar;49:37-43. doi: 10.1016/j.ejim.2018.01.023. Bar-Lev Schleider L1, Mechoulam R2, Lederman V3, Hilou M3, Lencovsky O4, Betzalel O3, Shbiro L4, Novack V5. Author information Abstract BACKGROUND: Cancer is a major public health problem as the leading cause of death. Palliative treatment aimed to alleviate pain and nausea in patients with advanced disease […]

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Endocannabinoid tone regulates human sebocyte biology.

J Invest Dermatol. 2018 Feb 28. pii: S0022-202X(18)30147-7. doi: 10.1016/j.jid.2018.02.022. [Epub ahead of print] Zákány N1, Oláh A1, Markovics A1, Takács E1, Aranyász A1, Nicolussi S2, Piscitelli F3, Allarà M3, Pór Á4, Kovács I4, Zouboulis CC5, Gertsch J2, Di Marzo V3, Bíró T6, Szabó T7. Author information Abstract We have previously shown that i) endocannabinoids […]

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[Cannabinoids for neuropathic pain management].

Ugeskr Laeger. 2018 Feb 26;180(9). pii: V08170602. [Article in Danish] Andersen LØ1, Enggaard TP, Højsted J. Author information Abstract Pharmacological treatment of neuropathic pain is associated with side effects and limited efficacy. Recently, the interest in cannabis-based medicine has led to legalisation of medical cannabis in some countries. The aim of this review is to […]

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Innovative Therapeutic Potential of Cannabinoid Receptors as Targets in Alzheimer’s disease and Less Well-Known Diseases.

Curr Med Chem. 2018 Feb 25. doi: 10.2174/0929867325666180226095132. [Epub ahead of print] Paez JA1, Campillo NE2. Author information Abstract The discovery of cannabinoid receptors at the beginning of the 1990s, CB1 being cloned in 1990 and CB2 cloned in 1993, and the availability of selective and potent cannabimimetics could only be justified by the existence […]

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Eco-friendly process combining acid-catalyst and thermomechanical pretreatment for improving enzymatic hydrolysis of hemp hurds.

Bioresour Technol. 2018 Feb 23;257:192-200. doi: 10.1016/j.biortech.2018.02.107. [Epub ahead of print] Semhaoui I1, Maugard T2, Zarguili I3, Rezzoug SA4, Zhao JQ2, Toyir J3, Nawdali M3, Maache-Rezzoug Z5. Author information Abstract The aim of this study was to investigate a pretreatment by combined H2SO4 acid-catalyst and thermomechanical process to improve hemicelluloses solubilization of hemp hurds and […]

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The current state and future perspectives of cannabinoids in cancer biology.

Cancer Med. 2018 Feb 23. doi: 10.1002/cam4.1312. [Epub ahead of print] Śledziński P1, Zeyland J1, Słomski R1,2, Nowak A1. Author information Abstract To date, cannabinoids have been allowed in the palliative medicine due to their analgesic and antiemetic effects, but increasing number of preclinical studies indicates their anticancer properties. Cannabinoids exhibit their action by a […]


Analytical and Pharmacological Challenges in Cannabis Research

Planta Med 2018; 84(04): 213 DOI: 10.1055/s-0044-101051 Editorial Georg Thieme Verlag KG Stuttgart · New York Jürg Gertsch Further Information Abstract Full Text Buy Article Permissions and Reprints The millennial history of the use of cannabis as crop, medicinal and recreational plant reads like a novel in which the most recent chapter is dedicated to the […]

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Medical marijuana laws and adolescent marijuana use in the United States: A systematic review and meta-analysis.

Addiction. 2018 Feb 22. doi: 10.1111/add.14136. [Epub ahead of print] Sarvet AL1,2, Wall MM1,2,3, Fink DS4, Greene E4, Le A2, Boustead AE5, Pacula RL6, Keyes KM1,4, Cerdá M7, Galea S8, Hasin DS1,2,4. Author information Abstract AIMS: To conduct a systematic review and meta-analysis of studies in order to estimate the effect of US medical marijuana […]

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Medical use of cannabis: Italian and European legislation.

Eur Rev Med Pharmacol Sci. 2018 Feb;22(4):1161-1167. doi: 10.26355/eurrev_201802_14405. Zaami S1, Di Luca A, Di Luca NM, Montanari Vergallo G. Author information Abstract This review illustrates some brief considerations of the medical use of cannabis recently issued in Italy. History and uses of cannabis throughout centuries and different countries are illustrated together with a description […]

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Analysis of trends in the prevalence of cannabis use in Canada, 1985 to 2015.

Health Rep. 2018 Feb 21;29(2):10-20. Rotermann M1, Macdonald R2. Author information Abstract BACKGROUND: The Canadian federal government has committed to legalize, regulate, and restrict non-medical cannabis use by adults in 2018. To prepare for monitoring the health, social and economic impacts of this policy change, a greater understanding of the long-term trends in the prevalence […]