Abstract
Aflatoxin B1 is a carcinogenic mycotoxin that frequently contaminates crops worldwide. Current research indicates that the use of natural extracts to combat mycotoxin contamination may represent an eco-friendly, sustainable strategy to ensure food safety. Although Cannabis sativa L. has long been known for its psychoactive cannabinoids, it is also rich in many other bioactive molecules. This study examines extracts from various organs of Cannabis sativa L. to determine their ability to limit aflatoxin production and growth of Aspergillus flavus. The results indicate that flower extract is most effective for limiting the synthesis of aflatoxin B1, leading to an almost-complete inhibition of toxin production at a concentration of 0.225 mg dry matter per gram of culture medium. Since flower extract is rich in phenolic compounds, its total antioxidant ability and radical-scavenging capacity are determined. Compared with other anti-aflatoxigenic extracts, the anti-oxidative potential of Cannabis sativa L. flower extract appears moderate, suggesting that its anti-mycotoxin effect may be related to other bioactive compounds.
Keywords: Aflatoxin B1, Antioxidant activity, Cannabis sativa L., Inhibition, Phenolic compounds
References
-
- Abi-Khattar AM, Rajha HN, Abdel-Massih RM (2019) Intensification of polyphenol extraction from olive. Antioxidants 8:227. https://doi.org/10.3390/antiox8070227 – DOI – PMC
-
- Ainsworth EA, Gillespie KM (2007) Estimation of total phenolic content and other oxidation substrates in plant tissues using Folin-Ciocalteu reagent. Nat Prot 2:875–877. https://doi.org/10.1038/nprot.2007.102 – DOI
-
- Ayofemi S, Adeyeye O (2020) Aflatoxigenic fungi and mycotoxins in foods: a review. Crit Rev Food Sci Nutr 60:709–721. https://doi.org/10.1080/10408398.2018.1548429 – DOI
-
- Bailly S, El Mahgubi A, Carvajal-Campos A, Lorber S, Puel O, Oswald IP, Bailly JD, Orlando B (2018) Occurrence and identification of Aspergillus section Flavi in the context of the emergence of aflatoxins in French maize. Toxins 10:525. https://doi.org/10.3390/toxins10120525 – DOI – PMC
-
- Ben Miri Y, Djenane D (2018) Evaluation of protective impact of algerian Cuminum cyminum L. and Coriandrum sativum L. essential oils on Aspergillus flavus growth and aflatoxin B1 production. Pak J Biol Sci 21:67–77. https://doi.org/10.3923/pjbs.2018.67.77 – DOI – PubMed