Abstract
We report 3 patients (age 8, 13 and 14 years) with drug-resistant epilepsy due to Rasmussen encephalitis treated with cannabidiol in addition to their current antiseizure medication (ASM). In all three patients we observed a positive effect, which seemed to surpass the efficacy that would be expected from a different fourth or fifth antiseizure drug used during the course of the disease.
Keywords: Cannabidiol, Drug resistant epilepsy, Epilepsy, Rasmussen encephalitis
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
Conflict of interest statement
Declaration of competing interest We disclose the following potential conflicts: A.M. Kaindl has served on advisory boards, received personal and institutional funding from GW pharma, Biogen, Avexis, PTC, Nutricia and Desitin outside the submitted work. F. Kühne, A. Tietze and C. Prager have no conflicts of interest to disclose.