Tag Archives: endocannabinoids
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[Significance of the endocannabinoid system in migraine].

Neuropsychopharmacol Hung. 2019 Mar;21(1):12-18. [Article in Hungarian] Gecse K1, Bagdy G, Juhasz G. Author information Abstract Based on the traditional pain-relieving effect of Cannabis species an endogenous cannabinoid like system was discovered in the human body. Endocannabinoids have important role in the homeostasis of the body, such as stress response and mood control, feeding behaviour, […]

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Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain.

Brain Behav Immun. 2019 Apr 3. pii: S0889-1591(18)31247-9. doi: 10.1016/j.bbi.2019.04.006. [Epub ahead of print] Guida F1, Boccella S2, Belardo C2, Iannotta M2, Piscitelli F3, De Filippis F4, Paino S2, Ricciardi F2, Siniscalco D2, Marabese I2, Luongo L2, Ercolini D4, Di Marzo V5, Maione S6. Author information Abstract Recent evidence points to the gut microbiota as […]

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Cannabinoid interventions for PTSD: Where to next?

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Apr 1. pii: S0278-5846(19)30034-X. doi: 10.1016/j.pnpbp.2019.03.017. [Epub ahead of print] Ney L1, Matthews A2, Bruno R2, Felmingham K3. Author information Abstract Cannabinoids are a promising method for pharmacological treatment of post-traumatic stress disorder (PTSD). Despite considerable research devoted to the effect of cannabinoid modulation on PTSD symptomology, there is not a […]

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Cocaine-Induced Reinstatement of Cocaine Seeking Provokes Changes in the Endocannabinoid and N-Acylethanolamine Levels in Rat Brain Structures.

Molecules. 2019 Mar 21;24(6). pii: E1125. doi: 10.3390/molecules24061125. Bystrowska B1, Frankowska M2, Smaga I3,4, Niedzielska-Andres E5, Pomierny-Chamioło L6, Filip M7. Author information Abstract There is strong support for the role of the endocannabinoid system and the noncannabinoid lipid signaling molecules, N-acylethanolamines (NAEs), in cocaine reward and withdrawal. In the latest study, we investigated the changes […]

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ABHD6: Its Place in Endocannabinoid Signaling and Beyond.

Trends Pharmacol Sci. 2019 Mar 7. pii: S0165-6147(19)30033-1. doi: 10.1016/j.tips.2019.02.002. [Epub ahead of print] Cao JK1, Kaplan J1, Stella N2. Author information Abstract The endocannabinoid (eCB) signaling system modulates neurotransmission and inflammation, among other physiological functions. Its newest member, α/β-hydrolase domain-containing 6 (ABHD6), has emerged as a promising therapeutic target to treat several devastating diseases, […]

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Endocannabinoid Signalling in Atherosclerosis and Related Metabolic Complications.

Thromb Haemost. 2019 Feb 15. doi: 10.1055/s-0039-1678738. [Epub ahead of print] Guillamat-Prats R1, Rami M1, Herzig S2,3,4, Steffens S1,5. Author information Abstract Endocannabinoids are a group of arachidonic acid-derived lipid mediators binding to cannabinoid receptors CB1 and CB2. An overactivity of the endocannabinoid system plays a pathophysiological role in the development of visceral obesity and […]

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Transient Receptor Potential Vanilloid 1 Modulates Central Inflammation in Multiple Sclerosis.

Front Neurol. 2019 Jan 29;10:30. doi: 10.3389/fneur.2019.00030. eCollection 2019. Stampanoni Bassi M1, Gentile A2, Iezzi E1, Zagaglia S3, Musella A4, Simonelli I5, Gilio L2, Furlan R6, Finardi A6, Marfia GA2, Guadalupi L4, Bullitta S2, Mandolesi G4, Centonze D1,2, Buttari F1. Author information Abstract Introduction: Disease course of multiple sclerosis (MS) is negatively influenced by proinflammatory […]

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The effects of cannabinoids on the endocrine system.

Endokrynol Pol. 2018;69(6):705-719. doi: 10.5603/EP.a2018.0072. Borowska M, Czarnywojtek A, Sawicka-Gutaj N, Woliński K1, Płazińska MT, Mikołajczak P, Ruchała M. Author information Abstract Cannabinoids are the derivatives of the cannabis plant, the most potent bioactive component of which is tetrahydrocannabinol (THC). The most commonly used drugs containing cannabinoids are marijuana, hashish, and hashish oil. These compounds […]

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Plants come to mind: Phytocannabinoids, endocannabinoids, and the control of seizures

Editorial – Free Access Jordan S. Farrell Ivan Soltesz First published: 27 December 2018 https://doi.org/10.1111/add.14540 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as […]

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Weight loss and improved mood after aerobic exercise training are linked to lower plasma anandamide in healthy people.

Physiol Behav. 2018 Dec 19. pii: S0031-9384(18)30825-4. doi: 10.1016/j.physbeh.2018.12.018. [Epub ahead of print] de Oliveira Belitardo A1, de Mello MT2, Tufik S3, Peres MFP4. Author information Abstract Anandamide, a major endocannabinoid, participates in energy metabolism homeostasis and neurobehavioral processes. In a secondary analyses of an open-label, randomized controlled trial, we investigated the long-term effect of […]