Tag Archives: endocannabinoids
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Cannabinoids in depressive disorders.

Life Sci. 2018 Oct 2. pii: S0024-3205(18)30604-0. doi: 10.1016/j.lfs.2018.09.058. [Epub ahead of print] Poleszak E1, Wośko S2, Sławińska K2, Szopa A2, Wróbel A3, Serefko A4. Author information Abstract Cannabis sativa is one of the most popular recreational and medicinal plants. Benefits from use of cannabinoid agents in epilepsy, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, and […]

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Endocannabinoids, exercise, pain, and a path to health with aging.

Mol Aspects Med. 2018 Oct 2. pii: S0098-2997(18)30035-9. doi: 10.1016/j.mam.2018.10.001. [Epub ahead of print] Watkins BA1. Author information Abstract Physical activity is an important lifestyle factor for growth, development, and sustained health throughout life. In recent years, the benefits of physical activity have drawn more attention to its physiological effects on the body, including well-being. […]

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2-arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction.

Cardiovasc Res. 2018 Sep 28. doi: 10.1093/cvr/cvy242. [Epub ahead of print] Schloss MJ1, Horckmans M1,2, Guillamat-Prats R1, Hering D1, Lauer E3, Lenglet S3, Weber C1,4,5, Thomas A3,6, Steffens S1,5. Author information Abstract AIMS: Myocardial infarction leads to an enhanced release of endocannabinoids and a massive accumulation of neutrophils and monocytes within the ischemic myocardium. These […]

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New insights on atherosclerosis: A cross-talk between endocannabinoid systems with gut microbiota.

J Cardiovasc Thorac Res. 2018;10(3):129-137. doi: 10.15171/jcvtr.2018.21. Epub 2018 Sep 27. Moludi J1,2, Alizadeh M1, Lotfi Yagin N1, Pasdar Y3, Nachvak SM3, Abdollahzad H3, Sadeghpour Tabaei A4. Author information Abstract The incidence of atherosclerosis is increasing rapidly all over the world. Inflammatory processes have outstanding role in coronary artery disease (CAD) etiology and other atherosclerosis […]

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Circulating Endocannabinoids Are Reduced Following Bariatric Surgery and Associated with Improved Metabolic Homeostasis in Humans.

Obes Surg. 2018 Sep 22. doi: 10.1007/s11695-018-3517-0. [Epub ahead of print] Azar S1, Sherf-Dagan S2,3,4, Nemirovski A1, Webb M2, Raziel A5, Keidar A6, Goitein D4,5,7, Sakran N5,8,9, Shibolet O2,4, Tam J10, Zelber-Sagi S11,12. Author information Abstract BACKGROUND: The endocannabinoid (eCB) system plays a key role in the development of obesity and its comorbidities. Limited information […]

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Endocannabinoid Metabolome Characterization of Transitional and Mature Human Milk.

Nutrients. 2018 Sep 12;10(9). pii: E1294. doi: 10.3390/nu10091294. Gaitán AV1, Wood JT2, Zhang F3, Makriyannis A4, Lammi-Keefe CJ5,6. Author information Abstract Recognized as the gold standard, human milk (HM) is an extremely complex yet fascinating biofluid tailored to meet an infant’s nutritional requirements throughout development. Endocannabinoids and endocannabinoid-like compounds (endocannabinoid metabolome, ECM) are endogenous lipid […]

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Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history.

J Ethnopharmacol. 2018 Sep 8. pii: S0378-8741(18)31661-1. doi: 10.1016/j.jep.2018.09.004. [Epub ahead of print] Bonini SA1, Premoli M1, Tambaro S2, Kumar A3, Maccarinelli G1, Memo M1, Mastinu A4. Author information Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Cannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies […]

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Glucocorticoid interactions with the dorsal striatal endocannabinoid system in regulating inhibitory avoidance memory.

Psychoneuroendocrinology. 2018 Aug 30;99:97-103. doi: 10.1016/j.psyneuen.2018.08.021. [Epub ahead of print] Siller-Pérez C1, Fuentes-Ibañez A2, Sotelo-Barrera EL3, Serafín N4, Prado-Alcalá RA5, Campolongo P6, Roozendaal B7, Quirarte GL8. Author information Abstract The endocannabinoid (eCB) system is highly stress sensitive and known to modulate memory formation of emotionally arousing experiences across different corticolimbic structures. eCB signaling within these […]

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The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss.

Front Cell Neurosci. 2018 Aug 21;12:271. doi: 10.3389/fncel.2018.00271. eCollection 2018. Ghosh S1, Sheth S1, Sheehan K2, Mukherjea D2, Dhukhwa A1, Borse V3, Rybak LP1,2, Ramkumar V1. Author information Abstract Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell […]

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Cannabinoid receptor-1 signaling contributions to sign-tracking and conditioned reinforcement in rats.

Psychopharmacology (Berl). 2018 Aug 14. doi: 10.1007/s00213-018-4993-6. [Epub ahead of print] Bacharach SZ1,2, Nasser HM1, Zlebnik NE1, Dantrassy HM1, Kochli DE1, Gyawali U1,2, Cheer JF1,2,3, Calu DJ4,5. Author information Abstract RATIONALE: Endocannabinoids (eCBs) are critical gatekeepers of dopaminergic signaling, and disrupting cannabinoidreceptor-1 (CB1) signaling alters DA dynamics to attenuate cue-motivated behaviors. Prior studies suggest that […]