Canna~Fangled Abstracts

A review on epilepsy, current treatments, and potential of medicinal plants as an alternative treatment

By August 15, 2023August 31st, 2023No Comments

Review

doi: 10.1007/s10072-023-07010-5.

Online ahead of print.
Affiliations 

Abstract

Epilepsy is considered common neurological diseases that threaten the lives of millions of people all around the world. Since ancient times, different forms of medications have been used to treat this condition. Adverse events associated with treatments and the residence time of available drugs caused to search for safer and more efficient therapies and drugs remain one of the major areas of research interest for scientists. As one of the therapeutics with fewer side effects, plants and their essential oils can be considered replacements for existing treatments. Medicinal plants have proven to be an effective natural source of antiepileptic drugs; most of them have their mechanism of action by affecting GABA receptors in different paths. Cannabis indica and Cymbopogon winterianus are well-known plant species with antiepileptic activities. The current review presenting a list of plants with antiepileptic effects aims to pave the way for finding alternative drugs with fewer side effects for scientists.

Keywords: Antiepileptic, Epilepsy, GABA, GABA receptors, Herbal medicines

References

    1. Ghosh S, Sinha JK, Khan T, Devaraju KS, Singh P, Vaibhav K, Gaur P (2021) Pharmacological and therapeutic approaches in the treatment of epilepsy. Biomedicines 9:470. https://doi.org/10.3390/biomedicines9050470 – DOI – PubMed – PMC
    1. Sirven JI (2015) Epilepsy: a spectrum disorder. Cold Spring Harb Perspect Med 5:a022848. https://doi.org/10.1101/cshperspect.a022848
    1. Edafiogho IO, Scott KR (1996) Anticonvulsants. In: Wolff E (ed) Burger’s Medicinal Chemistry and Drug Discovery, 5th edn. John Wiley & Sons, pp 175–260
    1. WHO (2023) Epilepsy. https://www.who.int/news-room/fact-sheets/detail/epilepsy . Accessed 3 January 2023
    1. Fisher RS (2017) The new classification of seizures by the international league against epilepsy 2017. Curr Neurol Neurosci Rep 17:48. https://doi.org/10.1007/s11910-017-0758-6 – DOI – PubMed

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