Canna~Fangled Abstracts

Cannabinoids for drug-resistant seizures in a critically ill patient-Case report and literature review.

By November 26, 2019 November 27th, 2019 No Comments
2019 Nov 26. doi: 10.1111/jcpt.13082.
[Epub ahead of print]

Abstract

WHAT IS KNOWN AND OBJECTIVE:

Drug-resistant seizures are life-threatening and contribute to sustained hospitalization. We present the case of a critically ill 28-year-old male with Lennox-Gastaut syndrome who had approximately 30 seizures/day in the intensive care unit.

CASE DESCRIPTION:

Patient required mechanical ventilation and pharmacologically induced thiopentone coma. He was commenced on cannabidiol and subsequently extubated. He remained seizure-free thereafter on a combination of cannabidiol and anti-epileptic medication that predated his critical illness.

WHAT IS NEW AND CONCLUSION:

Our case report provides a unique perspective on the role of cannabidiol in achieving remission from drug-resistant seizures in critically ill patients.

KEYWORDS: cannabidiol, cannabis, drug-resistant, epilepsy, neurology, seizures

PMID: 31770462
DOI: 10.1111/jcpt.13082

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