Edinb Med J. 1858 Apr; 3(10): 877–878.
PMCID: PMC5311814
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The medicine was first given in quarter grain, and afterwards in two grain doses, repeatedly hourly, until narcotism was induced. Strong soup, wine, and arrow-root were freely given.
The medicine produced marked relief, and was used freely — the quantity given daily varying from four to eighteen grains, and the child was kept almost constantly narcotized. The attacks of titanic spasm became gradually less severe; and, after twelve days, the medicine was discontinued, and the child recovered perfectly.